Calretinin Antibody

Images

 
Immunohistochemistry-Paraffin: Calretinin Antibody [NBP2-12450] - Human mesothelioma stained with Calretinin using peroxidase-conjugate and AEC chromogen. Note cytoplasmic and nuclear staining of tumor cells.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP2-12450
    • Availability
      Product Discontinued

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Calretinin Antibody Summary

Immunogen
Recombinant full-length mouse calretinin protein
Localization
Nuclear and cytoplasmic
Marker
Mesothelial Cell Marker
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CALB2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10 - 1:500
  • Immunohistochemistry-Paraffin 1:100

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
10mM PBS (pH 7.6) and 0.2% BSA
Preservative
15mM Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Calretinin Antibody

  • 29 kDa calbindin
  • CAB29
  • CAL2
  • CALB2
  • calbindin 2
  • calbindin 2, (29kD, calretinin)
  • calbindin 2, 29kDa (calretinin)
  • calbindin D29K
  • Calretinin
  • CR

Background

Calretinin is an intracellular calcium-binding protein belonging to the troponin C superfamily characterized by a structural motif described as the EF-hand domain. The immunohistochemical detection of calretinin in developing cerebellum is restricted to the later stages indicated by weak staining from week 21 of gestation, in Purkinje and basket cells and in neurons of the dentate nucleus. The intensity of staining increases as the cerebellum matures. In tumors, calretinin has been detected in mesotheliomas and some pulmonary adenocarcinomas.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for Calretinin Antibody (NBP2-12450)

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Blogs on Calretinin.

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While not life threatening, blindness and retinal disease are profoundly debilitating and greatly affect quality of life.  Understandably, gene therapy has been subject to controversy given it’s potential effects on the rest of our cellular...  Read full blog post.

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Bioinformatics

Gene Symbol CALB2
Entrez
Uniprot