Recombinant Human Calpain 1 Protein

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE

Order Details

Recombinant Human Calpain 1 Protein Summary

Description
Native Calpain 1

Source:Human Erythrocyte
Amino Acid Sequence:(P07384)

Protein/Peptide Type
Biologically Active Protein
Gene
CAPN1
Purity
>95%, by SDS-PAGE

Applications/Dilutions

Application Notes
Specific activity: >1000 units/mg protein
Theoretical MW
112 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Buffer
20 mM imidazole-HCl, 5 mM B-mercaptoethanol, 1 mM EDTA, 1 mM EGTA, 30% glycerol, pH 6.8.
Purity
>95%, by SDS-PAGE

Alternate Names for Recombinant Human Calpain 1 Protein

  • Calcium-activated neutral proteinase 1
  • calpain 1, (mu/I) large subunit
  • Calpain mu-type
  • calpain, large polypeptide L1
  • calpain-1 catalytic subunit
  • Calpain-1 large subunit
  • CANP 1
  • CANP
  • CANPL1EC 3.4.22.52
  • Cell proliferation-inducing gene 30 protein
  • cell proliferation-inducing protein 30
  • EC 3.4.22
  • micromolar-calpain
  • muCANPCANP1
  • muCL

Background

Ca2-dependent cysteine proteinase with low Ca2 requirement (half maximal activation = 2uM). Participates in the ATP release reaction of platelets stimulated with thrombin. Involves in apoptosis activation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 2 years from date of receipt.

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Bioinformatics

Gene Symbol CAPN1