Cadherin-16 Antibody

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Western Blot: cadherin-16 Antibody [NB100-92446] - Western blot (WB) analysis of cadherin-16 (M810) antibody in extracts from A549 cells

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-92446
    • Availability
      Product Discontinued

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Cadherin-16 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 791-840 of Human Cadherin-16.
Specificity
Cadherin-16 (M810) detects endogenous levels of Cadherin-16 (M810) protein.
Clonality
Polyclonal
Host
Rabbit
Gene
CDH16
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunocytochemistry/Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Western blot (WB) analysis of cadherin-16 (M810) pAb in extracts from A549 cells
Theoretical MW
90 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

This antibody is reactive against Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Cadherin-16 Antibody

  • cadherin 16, KSP-cadherin
  • cadherin-16
  • Kidney-specific cadherin
  • KSP-cadherin

Background

The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. cadherin-16, also known as Ksp-Cadherin, is a type I membrane protein which is kidney-specific. cadherin-16 is expressed exclusively in the basolateral membrane of renal tubular epithelial cells. The human Ksp-cadherin gene (cadherin-16) maps to chromosome 16q21-proximal 16q22. The mouse Ksp-cadherin gene was localized to a highly syntenic region of distal Chromosome 8.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CDH16
Entrez