CAD Antibody

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Western Blot: CAD Antibody [NBP1-52969] - Human Lung lysate, concentration 0.2-1 ug/ml.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-52969
    • Availability
      Product Discontinued

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CAD Antibody Summary

Immunogen
Synthetic peptides corresponding to CAD(carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase) The peptide sequence was selected from the C terminal of CAD. Peptide sequence ADVVVLRHPQPGAVELAAKHCRRPVINAGDGVGEHPTQ
Clonality
Polyclonal
Host
Rabbit
Gene
CAD
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
This is a rabbit polyclonal antibody against CAD and was validated on Western blot.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 2% Sucrose
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for CAD Antibody

  • CAD protein
  • CAD trifunctional protein
  • carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, anddihydroorotase
  • EC 2.1.3.2
  • EC 3.5.2.3
  • EC 6.3.5
  • EC 6.3.5.5
  • multifunctional protein CAD

Background

CAD is a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CAD Antibody (NBP1-52969) (0)

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Bioinformatics

Gene Symbol CAD
Uniprot