C1qTNF5/CTRP5 Antibody

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Western Blot: C1qTNF5/CTRP5 Antibody [NBP1-76425] - caco-2 cell lysate with CTRP5 antibody at (A) 1, (B) 2, and (C) 4 ug/ml.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-76425
    • Availability
      Product Discontinued

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C1qTNF5/CTRP5 Antibody Summary

Immunogen
Antibody was raised against a 15 amino acid synthetic peptide from near the center of human CTRP5. The immunogen is located within amino acids 90 - 140 of CTRP5.
Specificity
Adipokine proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.
Clonality
Polyclonal
Host
Rabbit
Gene
C1QTNF5
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
Application Notes
CTRP5 antibody can be used for the detection of CTRP5 by Western blot at 1 - 2 mg/ml. Caco-2 cell lysate can be used as positive control. CTRP5 antibody is human specific. Adipokine proteins are often highly modified post-translationally and migrate in SD

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for C1qTNF5/CTRP5 Antibody

  • C1q and tumor necrosis factor related protein 5
  • C1qTNF5
  • Complement C1q Tumor Necrosis Factor-Related Protein 5 Precursor Variant 3
  • CTRP5
  • CTRP5LORDDKFZp586B0621
  • LORD 6
  • Myonectin 3

Background

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. CTRP5 has been suggested to be involved in age-related macular degeneration.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol C1QTNF5
Entrez
Uniprot