BTK Antibody (1H7)

Images

 
Western Blot: BTK Antibody (1H7) [NBP2-02479] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BTK (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug ...read more
Immunocytochemistry/ Immunofluorescence: BTK Antibody (1H7) [NBP2-02479] Staining of COS7 cells transiently transfected by pCMV6-ENTRY BTK.
Immunohistochemistry-Paraffin: BTK Antibody (1H7) [NBP2-02479] - Staining of paraffin-embedded Kidney tissue using anti-BTK mouse monoclonal antibody.
Flow Cytometry: BTK Antibody (1H7) [NBP2-02479] - HEK293T cells transfected with either pCMV6-ENTRY BTK.(Red) or empty vector control plasmid (Blue) were immunostained with anti-BTK mouse monoclonal, and then analyzed ...read more
Immunohistochemistry-Paraffin: BTK Antibody (1H7) [NBP2-02479] - Staining of paraffin-embedded Carcinoma of liver tissue using anti-BTK mouse monoclonal antibody.

Product Details

Summary
Product Discontinued
View other related BTK Primary Antibodies

Order Details


    • Catalog Number
      NBP2-02479
    • Availability
      Product Discontinued

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BTK Antibody (1H7) Summary

Immunogen
Full length human recombinant protein of human BTK (NP_000052) produced in HEK293T cell.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
BTK
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000
  • Flow Cytometry 1:100
  • Immunocytochemistry/Immunofluorescence 1:100
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for BTK Antibody (1H7)

  • Agammaglobulinaemia tyrosine kinase
  • AGMX1
  • AGMX1MGC126262
  • AT
  • ATKIMD1
  • B-cell progenitor kinase
  • BPK
  • Bruton agammaglobulinemia tyrosine kinase
  • Bruton tyrosine kinase
  • BTK
  • dominant-negative kinase-deficient Brutons tyrosine kinase
  • EC 2.7.10
  • EC 2.7.10.2
  • IMD1
  • PSCTK1
  • tyrosine-protein kinase BTK
  • XLA
  • XLAMGC126261

Background

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional BTK Products

Bioinformatics Tool for BTK Antibody (NBP2-02479)

Discover related pathways, diseases and genes to BTK Antibody (NBP2-02479). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for BTK Antibody (NBP2-02479)

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Research Areas for BTK Antibody (NBP2-02479)

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Blogs on BTK.

CD79b - A Signal Transduction Component of the B-cell Receptor
The B-cell antigen receptor (BCR) is a complex multimeric aggregate that includes the following key noncovalently-bound components: antigen-specific surface immunoglobulin (Ig), CD79a (Ig-alpha), and CD79b (Ig-beta). BCR signaling is a pivotal pathway...  Read full blog post.

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Bioinformatics

Gene Symbol BTK
Entrez