BTBD7 Blocking Peptide

Images

 
There are currently no images for BTBD7 Protein (NBP1-49654).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Func
Concentration
2.5 mg/ml

Order Details

BTBD7 Blocking Peptide Summary

Description
Synthetic peptide corresponding to unique epitope on Btbd7 protein between aa 1095-1138. The peptide sequence selected was post synthetically modified to achieve desired antigenicity before covalently coupling to a carrier protein.

NCBI Accession #: NP_001002860

Source: Synthetic

Source
Synthetic
Protein/Peptide Type
Blocking Peptide
Gene
BTBD7
Purity
>85%, by HPLC

Applications/Dilutions

Application Notes
This peptide is useful as a blocking peptide for NBP1-49652. For further blocking peptide related protocol, click here. Applications: Immmunodepletion, Competition Assay
Theoretical MW
126 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Sodium Bicarbonate buffer, pH 8.00 containing up to 10% DMSO
Concentration
2.5 mg/ml
Purity
>85%, by HPLC

Alternate Names for BTBD7 Blocking Peptide

  • BTB (POZ) domain containing 7
  • DKFZp686N0544
  • FLJ10648
  • FUP1BTB/POZ domain-containing protein 7
  • KIAA1525
  • MGC48310

Background

Cancer cells especially human hepatocellular carcinoma (HCC) differentially express many genes as determined by cDNA microarrays. One of these genes is Btbd7 whose function was not known. When transfected in NIH3T3 cells this gene exhibited enhanced cell proliferation activity by MTT assay. The enhanced tumorigencity was blocked by anti-sense RNA experiments (1). Recently it has been shown that Btbd7 regulate epithelial cell dynamics and branching morphogenesis. The organ development during embryogenesis requires extensive branching of epithelia via formation of cleft and buds. These branches are developed by local outgrowth or by formation of cleft that further divide epithelia in to buds. The bud or tubule extension is controlled and regulated by various growth factors. These branching finally led to formation of various organs. Cellular matrix protein fibronectin is required for salivary, lung and kidney branching (3). The edges of fibronectin translocates inwards as cleft accompanied by loss of E-cadherin in cells adjacent to fibronectin. The Btbd7 activity was noticed at cell cleft forming sites (2). The cleft formation involves buds delineation of buds by conversion of epithelial cell-cell adhesion to cell-matrix adhesion. Btbd7 provides a mechanistic link between the extracellular matrix and cleft propagation via its highly discrete expression that control epithelial cell motility by interaction with other cellular architectural and scaffolding proteins like Snail2 (slug), E-cadherin (4). The Btbd7 antibodies were generated using peptide corresponding to C-terminal domain of the human Btbd7 gene. The Btbd7 antibodies are affinity purified over immobilized antigen based affinity chromatography, and the purified immunoglobulins are stabilized in antibody stabilization buffer. Antibodies to Btbd7 (Btbd-701AP) will label ~144kDa protein in Western blot positive control for Btbd7 (PC-Btbd7).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-03886
Species: Hu, Mu
Applications: WB, Flow, IHC, IHC-P
NB100-137
Species: Hu, Mu, Rt, Pm
Applications: WB, Simple Western, Flow, ICC/IF, IHC, IHC-P, IP
AF748
Species: Hu, Mu
Applications: WB, Simple Western, Flow, IHC, CyTOF-ready, ICC
NBP1-49654
Species: Hu
Applications: Func

Publications for BTBD7 Protein (NBP1-49654) (0)

There are no publications for BTBD7 Protein (NBP1-49654).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for BTBD7 Protein (NBP1-49654) (0)

There are no reviews for BTBD7 Protein (NBP1-49654). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

View specific protocols for BTBD7 Protein (NBP1-49654): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for BTBD7 Protein (NBP1-49654) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional BTBD7 Products

BTBD7 NBP1-49654

Bioinformatics Tool for BTBD7 Protein (NBP1-49654)

Discover related pathways, diseases and genes to BTBD7 Protein (NBP1-49654). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for BTBD7 Protein (NBP1-49654)

Discover more about diseases related to BTBD7 Protein (NBP1-49654).
 

Pathways for BTBD7 Protein (NBP1-49654)

View related products by pathway.

Blogs on BTBD7

There are no specific blogs for BTBD7, but you can read our latest blog posts.

Customers Who Bought This Also Bought

BTBD7 Antibody
NBP1-49652

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our BTBD7 Blocking Peptide and receive a gift card or discount.

Bioinformatics

Gene Symbol BTBD7