BST2 Antibody

Product Discontinued

BST2 Antibody Summary

• Immunogen: Synthetic peptide (Human).
• Localization: Extra cytoplasmic
• Specificity: Detects a band between 30-36kDa in BST2
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: BST2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Dot Blot 1:2000
  • ELISA 1:2000
  • Western Blot 1:500-1:1000
• Control:

  BST2 Overexpression Lysate

Reactivity Notes

Cross-reacts with Human, Rat, Mouse. Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Tris/Glycine buffer pH 7.5-7.9, stabilizing protein, and glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for BST2 Antibody

• bone marrow stromal antigen 2
• bone marrow stromal cell antigen 2
• BST2
• BST-2
• CD317 antigen
• CD317
• HM1.24 Antigen
• NPC-A-7
• PDCA-1
• Tetherin

Background

Bone marrow stromal Antigen-2 (BST-2) is a 30- to 36-kDa type II transmembrane protein, consisting of 180 amino acids. BST-2 protein is expressed on certain bone marrow stromal cell lines and on various normal tissues. The expression pattern of BST2 is relatively different form another bone marrow stromal antigen 1 (BST1). The BST-2 gene is located on chromosome 19p13.2. BST-2 surface expression on fibroblast cell lines facilitated the stromal cell-dependent growth of a murine bone marrow-derived pre-B-cell line, DW34. Some studies suggest that BST-2 may be involved in pre-B-cell growth development by regulating their surface molecules and cytokines (1). BST2 is also expressed in bone marrow stromal cell lines and synovial cell lines from where the BST2 gene was cloned. BST2 is predominantly expressed in liver, lungs, heart, placenta and lower levels in pancreas, kidney, skeletal muscle and brain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BST2
• Entrez:
  • 684(Human)