Human Breast Tissue MicroArray (Cancer)

Images

 
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 01. Breast infiltrating Duct Carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 02. Breast Infitrating Duct Carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 03. Breast Infiltrating Duct Carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 04. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 05. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 06. Prostate adenocarcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 07. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 08. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 09. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 10. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 11. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 12. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 13. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 14. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 15. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 21. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 22. Breast metaplastic carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 23. Breast, Infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 24. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 25. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 26. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 27. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 28. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 29. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 30. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 31. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 32. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 33. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 34. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 35. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 36. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 37. Breast, infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 38. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 39. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 40. Breast infiltrating duct carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 41. Lymph node, metastatic carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 42. Lymph node, metastatic carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 44. Lymph node, metastatic carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 45. Lymph node metastatic carcinoma from #35
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 46. Lymph node, Metastatic carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 47. Lymph node, Metastatic carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 48. Lymph node, Metastatic carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 49. Lymph node, Metastatic carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 50. Lymph node, metastatic carcinoma
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 51. Breast normal (match to 5)
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 52. Breast Normal
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 53. Breast Normal
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 54. Breast Normal
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 55. Breast normal (match to #11)
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 56. Breast Normal
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 57. Breast Normal
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 59. Breast normal (match to #35)
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 58. Breast normal (match to #34)
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 16. Breast infiltrating duct carcinoma T2N1miM0, Stage IIB.
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 17. Breast infiltrating duct carcinoma T2N1miM0, stage IIB.
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 18. Breast intraductal papillary carcinoma T2N0M0, stage IIA.
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 19. Breast infiltrating duct carcinoma T3N0M0, stage IIB.
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 20. Breast atypical medullary carcinoma T2N1aM0, stage IIB.
Hematoxylin & Eosin Stain: Human Breast Tissue MicroArray (Cancer) [NBP2-30212] - 43. Lymph node metastatic carcinoma from #33.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IHC-P

Order Details

Human Breast Tissue MicroArray (Cancer) Summary

Description
Microarray Panel:
Breast cancer-metastasis-normal
No. of samples 59
No. of patients 40
Core diameter 2.0 mm
Format:Formalin Fixed
Section thickness 4 micrometer
Core#
No.
Age Sex Organ Diagnosis pTNM Stage LN* Tissue
type
Image
1 59 F Breast infiltrating duct carcinoma T2N0M0 IIA 0/19 6
2 48 F Breast infiltrating duct carcinoma T2N0M0 IIA 0/16 6
3 42 F Breast infiltrating duct carcinoma T2N2aM0 IIIA 5/19 6
4 37 F Breast infiltrating duct carcinoma T2N2aM0 IIIA 8/8 6
5 37 F Breast infiltrating duct carcinoma T2N0M0 IIA 0/20 6
6 55 F Breast infiltrating duct carcinoma T2N0M0 IIA 0/19 6
7 55 F Breast infiltrating duct carcinoma T3N3aM0 IIIC 20/20 6
8 36 F Breast infiltrating duct carcinoma T3N0M0 IIB 0/14 6
9 52 F Breast infiltrating duct carcinoma T2N2aM0 IIIA 5/24 6
10 40 F Breast infiltrating duct carcinoma T2N0M0 IIA 0/11 6
11 51 F Breast infiltrating duct carcinoma T2N0M0 IIA 0/8 6
12 55 F Breast infiltrating duct carcinoma T2N0M0 IIA 0/19 6
13 60 F Breast infiltrating duct carcinoma T2N0M0 IIA 0/16 6
14 45 F Breast sarcomatoid carcinoma T2N1aM0 IIB 3/23 6
15 38 F Breast infiltrating duct carcinoma T3N1aM0 IIIA 3/13 6
16 53 F Breast infiltrating duct carcinoma T2N1miM0 IIB 3/14 6
17 48 F Breast infiltrating duct carcinoma T2N1miM0 IIB 2/15 6
18 46 F Breast intraductal papillary carcinoma T2N0M0 IIA 0/15 6
19 40 F Breast infiltrating duct carcinoma T3N0M0 IIB 0/10 6
20 51 F Breast atypical medullary carcinoma T2N1aM0 IIB 1/16 6
21 56 F Breast infiltrating duct carcinoma T2N0M0 IIA 0/14 6
22 45 F Breast metaplastic carcinoma T2N0M0 IIA 0/17 6
23 42 F Breast infiltrating duct carcinoma T2N3aM0 IIIC 12/26 6
24 47 F Breast infiltrating duct carcinoma T2N1miM0 IIB 1/11 6
25 39 F Breast infiltrating duct carcinoma T2N1aM0 IIB 2/17 6
26 51 F Breast infiltrating duct carcinoma T2N1aM0 IIB 1/13 6
27 49 F Breast infiltrating duct carcinoma T2N0M0 IIA 0/20 6
28 57 F Breast infiltrating duct carcinoma T3N1aM0 IIIA 3/7 6
29 52 F Breast infiltrating duct carcinoma T2N1aM0 IIB 1/22 6
30 41 F Breast infiltrating duct carcinoma T3N2aM0 IIIA 7/9 6
31 48 F Breast infiltrating duct carcinoma T2N3aM0 IIIC 35/35 6
32 34 F Breast infiltrating duct carcinoma T2N1aM0 IIB 2/11 6
33 37 F Breast infiltrating duct carcinoma T2N3aM0 IIIC 22/23 6
34 58 F Breast infiltrating duct carcinoma T2N3aM0 IIIC 19/22 6
35 37 F Breast infiltrating duct carcinoma T2N3aM0 IIIC 17/19 6
36 66 F Breast infiltrating duct carcinoma T2N2aM0 IIIA 4/11 6
37 51 F Breast infiltrating duct carcinoma T2N1aM0 IIB 3/16 6
38 41 F Breast infiltrating duct carcinoma T2N3aM0 IIIC 15/21 6
39 56 F Breast infiltrating duct carcinoma T3N2aM0 IIIA 5/13 6
40 47 F Breast infiltrating duct carcinoma T3N3aM0 IIIC 11/13 6
41 48 F Lymph node metastatic carcinoma from #31 . . . 6
42 34 F Lymph node metastatic carcinoma from #32 . . . 6
43 37 F Lymph node metastatic carcinoma from #33 . . . 6
44 58 F Lymph node metastatic carcinoma from #34 . . . 6
45 37 F Lymph node metastatic carcinoma from #35 . . . 6
46 66 F Lymph node metastatic carcinoma from #36 . . . 6
47 51 F Lymph node metastatic carcinoma from #37 . . . 6
48 41 F Lymph node metastatic carcinoma from #38 . . . 6
49 56 F Lymph node metastatic carcinoma from #39 . . . 6
50 47 F Lymph node metastatic carcinoma from #40 . . . 6
51 37 F Breast normal (match to #5) . . . 3
52 48 F Breast normal (match to #31) . . . 3
53 36 F Breast normal (match to #8) . . . 3
54 40 F Breast normal (match to #10) . . . 3
55 51 F Breast normal (match to #11) . . . 3
56 55 F Breast normal (match to #12) . . . 3
57 60 F Breast normal (match to #13) . . . 3
58 58 F Breast normal (match to #34) . . . 3
59 37 F Breast normal (match to #35) . . . 3
60 . . Carbon . . . . .


Tissue type*: see General information sheet

Applications/Dilutions

Application Notes
Use in Immunohistochemistry reported in scientific literature (PMID 27374178).
Publications
Read Publications using
NBP2-30212 in the following applications:

  • IHC
    3 publications
  • 4 publications
  • ISH
    1 publication

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.

Details for Breast

Type
Tissue
Tissue Condition
Cancer

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Tissue Micro Arrays are guaranteed for 1 year from date of receipt.

Publications for Breast Tissue Micro Array (NBP2-30212)(9)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: IHC, IHC-P, ISH.


Filter By Application
IHC
(3)
IHC-P
(4)
ISH
(1)
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Filter By Species
Human
(5)
All Species
Showing Publications 1 - 9 of 9.
Publications using NBP2-30212 Applications Species
Silva SV, Lima MA, Cella N et al. ADAMTS-1 Is Found in the Nuclei of Normal and Tumoral Breast Cells. PLoS ONE Nov 2 2016 [PMID: 27764205] (IHC, Human) IHC Human
Xie X, Tang Sc, Cai Y et al. Suppression of breast cancer metastasis through the inactivation of ADP-ribosylation factor 1. Oncotarget Aug 10 2016 [PMID: 27517156] (IHC) IHC
Silva TA, Smuczek B, Valadao IC et al. AHNAK enables mammary carcinoma cells to produce extracellular vesicles that increase neighboring fibroblast cell motility Oncotarget 2016 Jun 27 [PMID: 27374178] (IHC, Human) IHC Human
Sen S, Kawahara B, Gupta D et al. Role of Cystathionine beta- synthase in Human breast Cancer. Free Radic Biol Med 2015 Jun 4 [PMID: 26051168] (Human) Human
Zhou Y, Han C, Li D et al. Cyclin-dependent kinase 11(p110) (CDK11(p110)) is crucial for human breast cancer cell proliferation and growth. Sci Rep. 2015 May 20 [PMID: 25990212] (IHC-P)

Details:
Human Breast Tissue Microarray (Cancer)/ human tissue microarray containing 40 breast cancer tumor tissues and 9 paired normal breast tissues was used for IHC-P staining of CDK11(p110). See the full text for detailed IHC-P protocol and the data is shown in Figure 2.
IHC-P
Schmitt DC, Madeira da Silva L, Zhang W et al. ErbB2-intronic microRNA-4728: a novel tumor suppressor and antagonist of oncogenic MAPK signaling. Cell Death Dis. 2015 May 08 [PMID: 25950472] (IHC-P, ISH) IHC-P, ISH
Liu B, Tahk S, Yee KM et al. PIAS1 Regulates Breast Tumorigenesis through Selective Epigenetic Gene Silencing. PLoS ONE. 2014 Mar 3 [PMID: 24586797] (IHC-P, Human)

Details:
The Breast Tissue TMA (NBP2-30212) was used to detect PIAS1 expression in normal ducts, ductal carcinoma in situ, and invasive ductal carcinoma tissues, Figs 1A. PIAS1 is a nuclear protein that diffuses to the cytoplasm under formalin fixation conditions
IHC-P Human
Yoshida GJ, Saya H. et al. Inversed relationship between CD44 variant and c-Myc due to oxidative stress-induced canonical Wnt activation. Biochem. Biophys. Res. Commun. 2014 Jan 10 [PMID: 24333422] (IHC-P, Human)

Details:
48 year female breast cancer patient tissue with lymph node metastasis, Fig 3E.
IHC-P Human
Liu NN, Xi Y, Callaghan MU et al. SMAD4 is a potential prognostic marker in human breast carcinomas. Tumour Biol. 2014 Jan 1 [PMID: 23975369]

Details:
IHC (P): Fig S1, Tables S1 & S2. NBP2-30212/IMH-364 lot CBA3 was used in this study. Overall SMAD4 expression was significantly lower in breast cancer than in normal adjacent breast tissue.

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