BRCA2 Antibody (3E6)


Immunocytochemistry/ Immunofluorescence: BRCA2 Antibody (3E6) [NB600-445] - Analysis of paraformaldehyde-fixed HeLa, using BRCA2 antibody at 1:100 dilution.

Product Details

Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IP
1 mg/ml

BRCA2 Antibody (3E6) Summary

Amino acids 188-563 of human BRCA2 expressed in E. coli. BRCA2-BBA.
This antibody recognizes the BRCA2 gene product, a 390-kDa nuclear protein.
Protein G purified
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Packaging, Storage & Formulations

Store at -80C. Avoid freeze-thaw cycles.
Phosphate-buffered saline, pH 7.2
No Preservative
1 mg/ml
Protein G purified


Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
390 kDa

Reactivity Notes


Alternate Names for BRCA2 Antibody (3E6)

  • BRCA1/BRCA2-containing complex, subunit 2
  • BRCC2
  • breast and ovarian cancer susceptibility gene, early onset
  • breast cancer 2 tumor suppressor
  • breast cancer 2, early onset
  • breast cancer susceptibility protein BRCA2
  • breast cancer type 2 susceptibility protein
  • FACD
  • FAD
  • FAD1
  • FANCD1Fanconi anemia, complementation group D1
  • Fanconi anemia group D1 protein
  • GLM3
  • PNCA2


The BRCA2 antibody clone 3E6 recognizes the BRCA2 gene product, a 390kDa nuclear protein. The BRCA2 gene was originally isolated based on its importance in the predisposition of women to early-onset breast and ovarian cancers, suggesting mutations affect its tumor suppressor-like activity. Targeted disruption of the BRCA2 gene in mice and binding of Rad51 to its carboxyl terminus have indicated an involvement in DNA recombination and double strand break repair.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for BRCA2 Antibody (NB600-445) (0)

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Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NB600-445AF405
Alexa Fluor (R) 488 Labeled NB600-445AF488
Alexa Fluor (R) 647 Labeled NB600-445AF647
Alexa Fluor (R) 700 Labeled NB600-445AF700
Allophycocyanin Labeled NB600-445APC
DyLight 350 Labeled NB600-445UV
DyLight 405 Labeled NB600-445V
DyLight 405LS Labeled NB600-445V3
DyLight 488 Labeled NB600-445G
DyLight 680 Labeled NB600-445FR
DyLight 755 Labeled NB600-445IR
PE Labeled NB600-445PE
PerCP Labeled NB600-445PCP

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FANCD2 and DNA damage repair
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RAD51 is a recombinase protein encoded by RAD51 gene in humans. Human RAD51 family members are highly similar to bacterial RecA and yeast Rad51, both biochemically and structurally. It is a 339-amino acid protein that plays an important role in homolo...  Read full blog post.

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The DMC1 gene encodes a 36.7 kDa nuclear protein involved in meiotic homologous recombination. This recombinase is functionally related to the yeast RAD51 and E. coli RecA genes. In contrast to RAD51, which functions in both mitotic and meiotic recomb...  Read full blog post.

Rad51 Antibody Reveals a Canine Model for Human Breast Cancer
Our antibody catalog includes an extensive range of Rad51 antibody reagents. Encoded by the RAD51 gene, the Rad51 protein plays a vital role in DNA repair, interacting with several other proteins, including BRCA1 and BRCA2, to effect homologous recomb...  Read full blog post.

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Human cancer research is the largest research area in our antibody database, with new oncogenes and cell lines being added all the time.Cancer triggers come from many sources, with a worrying amount of evidence to suggest that chemicals we’re in con...  Read full blog post.

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We at Novus Biologicals have an extensive antibody databasedevoted to the 13 Fanconi anaemia complementation (FANC) genes, which are involved in the recognition and repair of damaged DNA.The core complex of 8 proteins (FANCA, B, C, E, F, G, L and M)...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol BRCA2

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