Human BMP-5 Recombinant Protein Summary
A disulfide-linked homodimeric protein consisting two 138 residues glycosylated chains and corresponding to amino acids Ala317 - His454 of BMP5 (P22003).
Source: CHO cell line
Lyophilized from 0.2 mm filtered concentrated solution in 4 mM HCl.
|Details of Functionality
The ED50, as determined by inducing alkaline phosphatase production using mouse ATDC5 cells, is less than 1.2 mg/mL.
| Protein/Peptide Type
Less than 1 EU/mg of the rHuBMP-5 as determined by LAL method.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Centrifuge prior to opening. Reconstitute with 4 mM HCl to a final concentration of 0.1 mg/ml. Further dilutions should be made in appropriately buffered solutions.
This lyophilized preparation is stable at 2-8 degrees C, but should be kept at -20 degrees C for long term storage, preferably desiccated. Upon reconstitution, the preparation is most stable at -20 to -80 degrees C, and can be stored for one week at 2-8 degrees C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 degrees C to -80 degrees C. Avoid repeated freeze/thaw cycles.
Alternate Names for Human BMP-5 Recombinant Protein
- bone morphogenetic protein 5
Bone Morphogenetic Protein-5 (BMP-5) is a TGF-b superfamily cytokine that forms 40 kDa disulfide-linked homodimers. It signals through hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. BMP-5 promotes chondrocyte proliferation and differentiation, ovarian granulosa cell proliferation, dopaminergic neuronal differentiation, and dendrite outgrowth.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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