BMP-3 Antibody

Images

 
Western Blot: BMP-3 Antibody [NBP1-51265] - Analysis of BMP-3 (E306) pAb at 1:500 dilutionLane1:Hela cell lysateLane2:HEK293T cell lysateLane3:Mouse liver tissue lysate
Immunohistochemistry-Paraffin: BMP-3 Antibody [NBP1-51265] - Analyzes of BMP-3 (E306) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.
Western Blot: BMP3 Antibody [NBP1-51265] - Analyzes of BMP3 (E306) pAb in extracts from HeLa cells.
Immunohistochemistry-Paraffin: BMP3 Antibody [NBP1-51265] - Analyzes of BMP3 (E306) pAb in paraffin-embedded human lung carcinoma tissue.

Product Details

Summary
Product Discontinued
View other related BMP-3 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-51265
    • Availability
      Product Discontinued

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BMP-3 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 261-310 of Human BMP-3.
Specificity
BMP-3 (E306) pAb detects endogenous levels of BMP-3 protein.
Clonality
Polyclonal
Host
Rabbit
Gene
BMP3
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Western blot (WB) analyzes of BMP-3 (E306) pAb in extracts from HeLa cells.
Immunohistochemistry (IHC) analyzes of BMP-3 (E306) pAb in paraffin-embedded human lung carcinoma tissue.
Theoretical MW
54 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for BMP-3 Antibody

  • BMP3
  • BMP-3
  • BMP3A
  • BMP-3A
  • bone morphogenetic protein 3 (osteogenic)
  • bone morphogenetic protein 3
  • Bone morphogenetic protein 3A
  • bone morphogenetic protein-3
  • Osteogenin

Background

Bone morphogenic proteins (BMPs) are members of the TGFbeta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGFbeta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Diseases for BMP-3 Antibody (NBP1-51265)

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Bioinformatics

Gene Symbol BMP3
Entrez