Recombinant BMP-2 Protein



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Recombinant BMP-2 Protein Summary

A partial protein corresponding to BMP2.
E. coli expressed amino acids Gln 283 - 396 Arg (accession# P12643).
Details of Functionality
This reagent has been tested in bioassays using the ATDC-5 cell line. The ED50, as measured by the dose-dependent induction of ATDC-5 cell proliferation, is 80 ng/ml, corresponding to a specific activity of 10^4Units/mg.
Protein/Peptide Type
Partial Recombinant Protein
Endotoxin Note
Less than 0.01 ng/ug cytokine as determined by the LAL assay.

Reactivity Notes

This protein was made to the human sequence.

Packaging, Storage & Formulations

Store at -80C. Avoid freeze-thaw cycles.
Sterile liquid, phosphate buffered saline, pH 7.2, with 1.0% BSA. 0.22 um filtered.
0.09% Sodium Azide


Purity: Greater than 95%, as determined by SDS-PAGE

Alternate Names for Recombinant BMP-2 Protein

  • BMP2
  • BMP-2
  • BMP-2A
  • BMP2ABone morphogenetic protein 2A
  • bone morphogenetic protein 2


Bone morphogenetic protein 2 (BMP-2) is a member of the TGF-beta superfamily. BMP-2 is synthesized as large precursor molecules that are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins. Chondrocyte proliferation, endochondrial bone formation, longitudinal bone growth, and bone and cartilage repair are all regulated by BMP-2. This protein also induces the maintenance and repair of colonic epithelium, as well as suppresses the synthesis and release of neuronal dopamine. Recombinant human BMP-2 produced in E.coli is a homodimeric, non-glycosylated, polypeptide containing 115 amino acids.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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FAQs for BMP-2 Protein (NBP1-43174). (Showing 1 - 1 of 1 FAQ).

  1. I am interested in Bone Morphogenic Protein 2 (BMP-2) for clinical trial in humans. I am using this protein in stem cells culture for future use in humans. Do you have BMP-2 in pharma grade that I can use for humans?
    • Our antibodies are for research purposes only unfortunately. I am sorry we cannot be of further help.

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Gene Symbol BMP2