Blood Group Lewis b Overexpression Lysate (Denatured)

Images

 
FUT3 transfected lysate.
Lane 1: FUT3 transfected lysate (39.82 KDa) Lane 2: Non-transfected lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB

Order Details

Blood Group Lewis b Overexpression Lysate (Denatured) Summary

Description
Pasmid: pCMV-FUT3 full-length
Gene
FUT3

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for Blood Group Lewis b

Type
Overexpression
Protein State
Denatured

Notes

Quality control test: Transient overexpression cell lysate was tested with Anti-FUT3 antibody by Western Blots.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Blood Group Lewis b Overexpression Lysate (Denatured)

  • alpha-(1,3/1,4)-fucosyltransferase
  • Blood group Lewis alpha-4-fucosyltransferase
  • CD174
  • EC 2.4.1
  • EC 2.4.1.65
  • FT3B
  • fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
  • Fucosyltransferase 3
  • Fucosyltransferase III
  • FucT-III
  • galactoside 3(4)-L-fucosyltransferase
  • LEfucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood groupincluded)
  • Les
  • Lewis FT
  • MGC131739

Background

The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol FUT3