Blk Antibody

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Western Blot: BLK Antibody [NBP1-50677] - Mouse kidney tissue lysate.

Product Details

Summary
Product Discontinued
View other related Blk Primary Antibodies

Order Details


    • Catalog Number
      NBP1-50677
    • Availability
      Product Discontinued

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Blk Antibody Summary

Immunogen
Synthetic peptide surrounding amino acid 30 of mouse BLK
Clonality
Polyclonal
Host
Rabbit
Gene
BLK
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Western blot analysis (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody detects 27 kDa BLK in samples of mouse origin. Mouse liver and kidney extracts can be used as positive controls.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2), 1.0% BSA and 50% Glycerol
Preservative
0.02% Thimerosal
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Blk Antibody

  • B lymphocyte kinase
  • B lymphoid tyrosine kinase
  • BLK nonreceptor tyrosine kinase
  • Blk
  • EC 2.7.10.2
  • MGC10442
  • MODY11
  • p55-Blk
  • tyrosine-protein kinase Blk

Background

BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56KDa), belongs to the Src non-receptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional Blk Products

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Bioinformatics

Gene Symbol BLK
Entrez
Uniprot