beta-TrCP1/BTRC Antibody (1D4)

Images

 
Western Blot: betaTrCP Antibody (1D4) [NBP2-03657] HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY betaTrCP (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell ...read more

Product Details

Summary
Product Discontinued
View other related beta-TrCP1/BTRC Primary Antibodies

Order Details


    • Catalog Number
      NBP2-03657
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

beta-TrCP1/BTRC Antibody (1D4) Summary

Immunogen
Human fragment corresponding to amino acids 52-372 of human BTRC (NP_378663) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
BTRC
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for beta-TrCP1/BTRC Antibody (1D4)

  • beta-transducin repeat containing
  • betaTrCP
  • BETA-TRCP
  • betaTrCP1
  • beta-TrCP1
  • BTRC
  • BTRCP
  • bTrCP1
  • E3RSIkappaB
  • F-box and WD repeats protein beta-TrCP
  • F-box/WD repeat-containing protein 1A
  • FBW1A
  • FBXW1
  • FBXW1A
  • FBXW1ABTRCP
  • FWD1
  • MGC4643
  • pIkappaBalpha-E3 receptor subunit

Background

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class; in addition to an F-box, this protein contains multiple WD-40 repeats. This protein is homologous to Xenopus bTrCP1, yeast Met30, Neurospora Scon2 and Drosophila Slimb proteins. It interacts with HIV-1 Vpu and connects CD4 to the proteolytic machinery. It also associates specifically with phosphorylated IkappaBalpha and beta-catenin destruction motifs, probably functioning in multiple transcriptional programs by activating the NF-kappaB pathway and inhibiting the beta-catenin pathway. [provided by RefSeq].

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-54467
Species: Hu, Mu, Rt, Ch, Pm
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P, IP
NBP2-29323
Species: Hu, Mu, Rt, Bv, Ca, Ch, Xp
NBP2-21037
Species: Hu
Applications: WB, IHC, IHC-P
NBP1-59068
Species: Hu
Applications: WB
NBP1-81988
Species: Hu
Applications: IHC, IHC-P
NB120-1868
Species: Hu, Mu
Applications: WB, IHC, IHC-Fr, IHC-P, IP
NBP2-37539
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC
NB100-56507
Species: Hu, Mu, Rt
Applications: WB, Simple Western, Flow, ICC/IF, IHC, IHC-P, IP, CyTOF-ready
NBP1-89150
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
H00011026-M01
Species: Hu
Applications: WB, ELISA
NBP1-31302
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-16454
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
NB100-91662
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-54467
Species: Hu, Mu, Rt, Ch, Pm
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P, IP

Publications for beta-TrCP1/BTRC Antibody (NBP2-03657) (0)

There are no publications for beta-TrCP1/BTRC Antibody (NBP2-03657).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for beta-TrCP1/BTRC Antibody (NBP2-03657) (0)

There are no reviews for beta-TrCP1/BTRC Antibody (NBP2-03657). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for beta-TrCP1/BTRC Antibody (NBP2-03657) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional beta-TrCP1/BTRC Products

Bioinformatics Tool for beta-TrCP1/BTRC Antibody (NBP2-03657)

Discover related pathways, diseases and genes to beta-TrCP1/BTRC Antibody (NBP2-03657). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for beta-TrCP1/BTRC Antibody (NBP2-03657)

Discover more about diseases related to beta-TrCP1/BTRC Antibody (NBP2-03657).
 

Pathways for beta-TrCP1/BTRC Antibody (NBP2-03657)

View related products by pathway.

PTMs for beta-TrCP1/BTRC Antibody (NBP2-03657)

Learn more about PTMs related to beta-TrCP1/BTRC Antibody (NBP2-03657).
 

Research Areas for beta-TrCP1/BTRC Antibody (NBP2-03657)

Find related products by research area.

Blogs on beta-TrCP1/BTRC

There are no specific blogs for beta-TrCP1/BTRC, but you can read our latest blog posts.

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our beta-TrCP1/BTRC Antibody (1D4) and receive a gift card or discount.

Bioinformatics

Gene Symbol BTRC
Entrez