beta-NGF Antibody (JKhNGF-1)

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ELISA: beta-NGF Antibody (JKhNGF-1) [NBP1-48783] - ELISA Capture: The purified JKhNGF-1 antibody is useful as the capture antibody in a sandwich ELISA assay, when used in conjunction with the biotinylated JKhNGF-2 ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-48783
    • Availability
      Product Discontinued

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beta-NGF Antibody (JKhNGF-1) Summary

Immunogen
This antibody was generated by immunizing host with recombinant human NGF (a.a. 58-68)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
NGF
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA 6-10 ug/ml
Application Notes
For ELISA: We recommend the usage of Tris-Buffered Saline (TBS), pH = 7.2 for all washes and incubations, except substrate buffer. Do not use PBS as results may vary dramatically. Additional reported applications include: neutralization.

Reactivity Notes

Human. Cross-Reactivity Cattle (Bovine, Cow), Viper

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.2)
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for beta-NGF Antibody (JKhNGF-1)

  • Beta nerve growth factor precursor
  • beta-nerve growth factor
  • betaNGF
  • beta-NGF
  • HSAN5
  • MGC161426
  • nerve growth factor (beta polypeptide)
  • nerve growth factor, beta subunit
  • NGFB
  • NGFBMGC161428

Background

Nerve growth factor (NGF) stimulates division and differentiation of sympathetic and embryonic sensory neurons. NGF is thought to have a profound effect on the development and maintenance of sympathetic and embryonic sensory neurons (1). NGF activity isolated from the male mouse submaxillary gland (MSG) consists of three types of subunits, alpha, beta and gamma, which specifically interact to form a 7S, approximately 130,000-molecular weight (Mr) complex. The 7S complex contains two identical 118-amino acid beta-chains, which are solely responsible for the nerve growth-stimulating activity of NGF. While NGF is found in almost all vertebrates, most research has focused on murine NGF, as the mouse male submaxillary gland contains higher levels of this polypeptide than other tissues (2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol NGF
Entrez
Uniprot