beta-Catenin Antibody



Product Details

Product Discontinued
View other related beta-Catenin Primary Antibodies

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beta-Catenin Antibody Summary

Synthesized non-phosphopeptide derived from human beta-Catenin around the phosphorylation site of serine 37 (I-H-SP-G-A).
Epithelial Cell Marker, Adherens Junction Marker
Endogenous levels of total beta-Catenin protein.
Immunogen affinity purified
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Packaging, Storage & Formulations

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol.
0.02% Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Reactivity Notes

Human. Predicted cross-reactivity to Mouse and Rat.


Beta-catenin is an adherens junction protein, which mediates cell-cell adhesion, cell-cell communication and contributes to cytoskeletal integrity. It is similar to the product of the Drosophila segment polarity gene armadillo. Like armadillo, beta-catenin is part of the E cadherin multiprotein complex that regulates pattern formation at several stages of embryogenesis. In addition beta-catenin is involved in wound healing and tumor cell metastasis. Beta-catenin is part of the Wnt signaling cascade. It interacts with Tcf and Lef to activate gene transcription and regulates cell growth. Beta-catenin accumulation has been observed in various cancers, especially in colorectal tumors and hepatoblastoma. Beta-catenin-mediated transcription is down regulated when the protein binds to the tumor suppressor protein APC.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Contact Information

Product PDFs


Gene Symbol CTNNB1

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