beta-Catenin Antibody

Images

 
Western Blot: beta-Catenin Antibody [NB100-92332] - Extracts from HeLa cells and raw264.7 cells.
Immunohistochemistry: beta-Catenin Antibody [NB100-92332] - Catenin-beta (F660) antibody in paraffin-embedded human breast carcinoma tissue.
Western Blot: beta-Catenin Antibody [NB100-92332] - Antibody in extracts from HeLa cells.

Product Details

Summary
Product Discontinued
View other related beta-Catenin Primary Antibodies

Order Details


    • Catalog Number
      NB100-92332
    • Availability
      Product Discontinued

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beta-Catenin Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 640-690 of Human Catenin-beta.
Marker
Epithelial Cell Marker, Adherens Junction Marker
Clonality
Polyclonal
Host
Rabbit
Gene
CTNNB1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunocytochemistry/Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Western blot (WB) analysis of Catenin-Beta1 (F660) pAb in extracts from HeLa cells and raw264.7 cells.
Immunohistochemistry (IHC) analyzes of Catenin-Beta1 (F660) pAb in paraffin-embedded human breast carcinoma tissue.
Theoretical MW
92 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Positive Control
beta-Catenin Lysate (NBL1-09577)

Reactivity Notes

Cross reacts with Human, Mouse and Rat.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
15mM Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for beta-Catenin Antibody

  • bCatenin
  • beta 1 (88kD)
  • beta-Catenin
  • catenin (cadherin-associated protein), beta 1, 88kDa
  • catenin beta-1
  • CTNNB
  • CTNNB1
  • DKFZp686D02253
  • FLJ25606
  • FLJ37923

Background

The catenins, alpha, beta and gamma, are proteins which bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. alpha-catenin was initially described as an E-cadherin associated protein, and since has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. beta-catenin has also been found in complexes with the tumor suppressor protein APC. gamma-catenin, also known as plakoglobin, is a protein that binds with alpha-catenin and N-cadherin. It has been shown that the transmembrane phosphatase PTPmu associates with catenin/cadherin complexes and may regulate complex signaling.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for beta-Catenin Antibody (NB100-92332) (0)

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for beta-Catenin Antibody (NB100-92332)

Discover related pathways, diseases and genes to beta-Catenin Antibody (NB100-92332). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Bioinformatics

Gene Symbol CTNNB1
Entrez