beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody (HCD57)

Images

 
Flow Cytometry: beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody (HCD57) [NB100-78053] - Analysis using the Biotin conjugate of NB100-78053. Staining of Human peripheral blood lymphocytes with biotinylated HCD57, ...read more
Flow Cytometry: beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody (HCD57) [NB100-78053] - Human peripheral blood lymphocytes stained with purified HCD57, followed by anti-mouse IgGs FITC
Flow Cytometry: beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody (HCD57) [NB100-78053] - Analysis using the FITC conjugate of NB100-78053. Staining of Human peripheral blood lymphocytes with HCD57 FITC.

Order Details


    • Catalog Number
      NB100-78053
    • Availability
      Product Discontinued

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beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody (HCD57) Summary

Immunogen
The immunogen was the full length version of the protein: B2GAT1
Specificity
CD57 (HCD57)
Isotype
IgM Kappa
Clonality
Monoclonal
Host
Mouse
Gene
B3GAT1
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
Application Notes
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 1.0 microgram per one million cells in 100 microliter volume or 100 microliter of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Positive Control
beta-1,3-Glucuronyltransferase 1/B3GAT1 Lysate (NBL1-07881)

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.2)
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody (HCD57)

  • B3GAT1
  • beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
  • Beta-1,3-glucuronyltransferase 1
  • CD57
  • EC 2.4.1.135
  • galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1
  • GLCATP
  • GlcAT-P
  • GLCATPGLCUATP
  • GLCUATP
  • glcUAT-P
  • Glucuronosyltransferase P
  • HNK1
  • LEU7
  • NK1
  • NK-1
  • UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase

Background

B3GAT1, also known as HNK-1, NK-1, and Leu-7, is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. B3GAT1 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells and is also expressed on neural cells and striated muscle. B3GAT1 is not expressed on red cells, granulocytes, monocytes, or platelets.While the function of B3GAT1 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that B3GAT1 may be involved in cell-matrix interactions. B3GAT1 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants). The HCD57 antibody has been shown to recognize human B3GAT1 and to be useful for flow cytometry.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol B3GAT1
Entrez