Bestrophin 3 Antibody (3D7)

Images

 
Western Blot: Bestrophin 3 Antibody (3D7) [NBP2-03398] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Bestrophin 3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of ...read more
Immunocytochemistry/ Immunofluorescence: Bestrophin 3 Antibody (3D7) [NBP2-03398] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY Bestrophin 3.
Flow Cytometry: Bestrophin 3 Antibody (3D7) [NBP2-03398] - HEK293T cells transfected with either overexpression plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-Bestrophin 3 antibody, and ...read more
Flow Cytometry: Bestrophin 3 Antibody (3D7) [NBP2-03398] - Analysis of Jurkat cells, using anti-Bestrophin 3 antibody, (Red), compared to a nonspecific negative control antibody (Blue).

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP2-03398
    • Availability
      Product Discontinued

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Bestrophin 3 Antibody (3D7) Summary

Immunogen
Full length human recombinant protein of human BEST3 (NP_689652) produced in HEK293T cell.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
BEST3
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000
  • Flow Cytometry 1:100
  • Immunocytochemistry/Immunofluorescence 1:100

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Bestrophin 3 Antibody (3D7)

  • bestrophin 3
  • bestrophin-3
  • MGC13168
  • MGC40411
  • vitelliform macular dystrophy 2-like 3
  • VMD2L3Vitelliform macular dystrophy 2-like protein 3

Background

BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al., 2003 [PubMed 12907679]).[supplied by OMIM].

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Additional Bestrophin 3 Products

Bioinformatics Tool for Bestrophin 3 Antibody (NBP2-03398)

Discover related pathways, diseases and genes to Bestrophin 3 Antibody (NBP2-03398). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for Bestrophin 3 Antibody (NBP2-03398)

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Pathways for Bestrophin 3 Antibody (NBP2-03398)

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Blogs on Bestrophin 3.

"I can see clearly now": Targeting Bestrophin 1 to treat Bestrophinopathies
Encoded by the VMD2 gene on chromosome 11q13 Bestrophin 1 is the prototypic member of the RFP family of proteins which are more commonly called "bestrophins". The protein family was originally identified in Caenorhabditis elegans based on a conserved...  Read full blog post.

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Bioinformatics

Gene Symbol BEST3
Entrez