Bestrophin 2 RNAi

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications RNAi, RNAi SP

Order Details

Bestrophin 2 RNAi Summary

Specificity
vitelliform macular dystrophy 2-like 1 (VMD2L1), mRNA
Gene
BEST2

Applications/Dilutions

Application Notes
This RNAi causes protein knockdown.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Bestrophin 2 RNAi

  • bestrophin 2
  • FLJ20132
  • vitelliform macular dystrophy 2-like 1
  • Vitelliform macular dystrophy 2-like protein 1
  • VMD2L1bestrophin-2
  • VMD2-like gene 1

Background

Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. RNAi are guaranteed for 3 months from date of receipt.

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Publications for Bestrophin 2 RNAi (H00054831-R01) (0)

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Bioinformatics Tool for Bestrophin 2 RNAi (H00054831-R01)

Discover related pathways, diseases and genes to Bestrophin 2 RNAi (H00054831-R01). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on Bestrophin 2.

"I can see clearly now": Targeting Bestrophin 1 to treat Bestrophinopathies
Encoded by the VMD2 gene on chromosome 11q13 Bestrophin 1 is the prototypic member of the RFP family of proteins which are more commonly called "bestrophins". The protein family was originally identified in Caenorhabditis elegans based on a conserved...  Read full blog post.

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Bioinformatics

Gene Symbol BEST2