BCAP31 Antibody

Images

 
Western Blot: BCAP31 Antibody [NBP1-77249] - Ramos cell lysate with BAP31 antibody at (A) 0.5, (B) 1 and (C) 2ug/ml.
Immunohistochemistry-Paraffin: BCAP31 Antibody [NBP1-77249] - Rat lung tissue with BAP31 antibody at 2 ug/ml.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-77249
    • Availability
      Product Discontinued

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BCAP31 Antibody Summary

Immunogen
Antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human BAP31. The immunogen is located within the last 50 amino acids of BAP31.
Clonality
Polyclonal
Host
Rabbit
Gene
BCAP31
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunofluorescence
Application Notes
BAP31 antibody can be used for the detection of BAP31 by Western blot at 0.5 - 1 mg/ml.

Reactivity Notes

Human, Mouse, Rat

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for BCAP31 Antibody

  • 6C6-Ag
  • BAP31
  • Bap31,6C6-AG
  • BAP31DXS1357ECDM
  • BCAP31
  • B-cell receptor-associated protein 31
  • BCR-associated protein 31
  • BCR-associated protein Bap31,6C6-AG tumor-associated antigen
  • p28 Bap31,6C6-Ag
  • p28
  • Protein CDM

Background

Bap31 and the related protein Bap29 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family. These two proteins are highly homologous and can form homo- and heterodimers. Bap31 is thought to be involved in the intracellular trafficking of several molecules such as MHC Class I molecules and CD11b/CD18. It may also play a role in the initiation of ER stress-induced apoptosis through its association with caspase-8 via a death effector domain in its cytoplasmic tail, possibly through the promotion of membrane fragmentation and the release of cytochrome c from mitochondria. Bap31 itself contains two caspase cleavage sites and is cleaved during apoptosis. The p20 fragment of Bap31, when expressed ectopicially, is also a potent inducer cell death.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol BCAP31
Entrez
Uniprot