BCAP31 Antibody

Images

 
Western Blot: BCAP31 Antibody [NBP1-32296] - Sample(30 ug of whole cell lysate)A:293T B:A431 C:H129912% SDS PAGE, antibody diluted at 1:500.
Immunocytochemistry/ Immunofluorescence: BCAP31 Antibody [NBP1-32296] - Paraformaldehyde-fixed HeLa, using antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: BCAP31 Antibody [NBP1-32296] - Paraffin-embedded SW480 xenograft, using antibody at 1:100 dilution.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-32296
    • Availability
      Product Discontinued

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BCAP31 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human BCAP31. The exact sequence is proprietary.
Localization
Endoplasmic reticulum membrane, Endoplasmic reticulum-Golgi intermediate compartment membrane
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BCAP31
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunocytochemistry/Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.34 mg/ml
Purity
Immunogen affinity purified

Alternate Names for BCAP31 Antibody

  • 6C6-Ag
  • BAP31
  • Bap31,6C6-AG
  • BAP31DXS1357ECDM
  • BCAP31
  • B-cell receptor-associated protein 31
  • BCR-associated protein 31
  • BCR-associated protein Bap31,6C6-AG tumor-associated antigen
  • p28 Bap31,6C6-Ag
  • p28
  • Protein CDM

Background

BAP31 (B Cell Receptor Associated Protein, 28 kDa) is a multiple membrane spanning protein of the endoplasmic reticulum. It has been shown to form both homo and hetero oligomers with the closely related BAP29, and is a potential apoptotic regulator as a predicted BCL2/BCLXL associated protein. In the C terminal domain of BAP31, there are two identical recognition sites for initiator Caspases 1 and 8 of the programmed death cascade. It is hypothesized that BAP31 plays a role in the transport of selected proteins to the Golgi apparatus. BAP31 has also been shown to control expression of CFTR (cystic fibrosis transmembrane conductance regulator). It is believed that interference with the expression or function of BAP31 in epithelial cells may be a way to circumvent the chloride channel defect in cystic fibrosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol BCAP31
Entrez