BAIAP2 Overexpression Lysate (Denatured)

Images

 
BAIAP2 transfected lysate.
Lane 1: BAIAP2 transfected lysate (60.83 KDa) Lane 2: Non-transfected lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB

Order Details

BAIAP2 Overexpression Lysate (Denatured) Summary

Description
Pasmid: pCMV-BAIAP2 full-length
Gene
BAIAP2

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for BAIAP2

Type
Overexpression
Protein State
Denatured

Notes

Quality control test: Transient overexpression cell lysate was tested with Anti-BAIAP2 antibody by Western Blots.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for BAIAP2 Overexpression Lysate (Denatured)

  • BAI1-associated protein 2IRS-58
  • BAI-associated protein 2
  • BAP2
  • brain-specific angiogenesis inhibitor 1-associated protein 2
  • Fas ligand-associated factor 3
  • FLAF3
  • Insulin receptor substrate p53
  • Insulin receptor substrate p53/p58
  • Insulin receptor substrate protein of 53 kDa
  • IRSP53
  • IRSp53/58
  • Protein BAP2

Background

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Video Protocols

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Bioinformatics

Gene Symbol BAIAP2