Recombinant Human BAFF Receptor Protein

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
Lyoph

Order Details

Recombinant Human BAFF Receptor Protein Summary

Description
Recombinant bioactive protein containing 76 amino acids for Human BAFF Receptor

Source:E. coli
Amino Acid Sequence:(Q96RJ3)

Details of Functionality
Determined by its ability to block BAFF induced mouse splenocyte survival. The expected ED50 for this effect is typically 1-5 ug/ml in the presence of 1 ug/ml human soluble BAFF.
Source
E. coli
Protein/Peptide Type
Biologically Active Protein
Gene
TNFRSF13C
Purity
>95%, by SDS-PAGE
Endotoxin Note
<0.1 ng/ug

Applications/Dilutions

Theoretical MW
7.7 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Buffer
Sterile filtered and lyophilized from a solution containing 20 mM phosphate buffer, pH 8.0, and 500 mM NaCl.
Concentration
Lyoph
Purity
>95%, by SDS-PAGE
Reconstitution Instructions
Reconstitute in sterile H2O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers or stored at 4C for 1 week or -20C for future use.

Alternate Names for Recombinant Human BAFF Receptor Protein

  • B cell-activating factor receptor
  • BAFF receptor
  • BAFF-R
  • BAFFRMGC138235
  • B-cell-activating factor receptor
  • BLyS receptor 3
  • BR3
  • CD268 antigen
  • CD268
  • CVID4
  • tumor necrosis factor receptor superfamily member 13C
  • tumor necrosis factor receptor superfamily, member 13C

Background

BAFF Receptor (BAFFR), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFFR is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFFR/BAFF signaling plays a critical role in B cell survival and maturation. Recombinant human BAFFR is a 76 amino acid polypeptide (7.7 kDa) corresponding to the extraCellular portion of the full BAFFR protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 2 years from date of receipt.

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Bioinformatics

Gene Symbol TNFRSF13C