BAFF Receptor Antibody

Images

 
Western Blot: BAFF Receptor Antibody [NBP1-77234] - Human (H), mouse (M), and rat (R) spleen tissue lysates with BAFF Receptor antibody at 5 ug/ml.
Immunocytochemistry/ Immunofluorescence: BAFF Receptor Antibody [NBP1-77234] - Staining of BAFF-R in human spleen tissue with BAFF-R antibody at 20 ug/ml.
Immunohistochemistry: BAFF Receptor Antibody [NBP1-77234] - Staining of human spleen tissue with antibody at 5 ug/mL.
Immunohistochemistry-Paraffin: BAFF Receptor Antibody [NBP1-77234] - Human tonsil tissue with BAFF Receptor antibody at 5 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P, ICC, IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

BAFF Receptor Antibody Summary

Immunogen
Antibody was raised against a synthetic peptide corresponding to 15 amino acids near the carboxy terminus of human BAFF Receptor The peptide sequence is identical between human and mouse origin. The immunogen is located within the last 50 amino acids of BAFF Receptor.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TNFRSF13C
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunocytochemistry
  • Immunofluorescence
Application Notes
BAFF Receptor antibody can be used for detection of BAFF Rexeptor by Western blot at 2 to 5 mg/ml.
Theoretical MW
20 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
BAFF Receptor Peptide (NBP1-77234PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for BAFF Receptor Antibody

  • B cell-activating factor receptor
  • BAFF receptor
  • BAFF-R
  • BAFFRMGC138235
  • B-cell-activating factor receptor
  • BLyS receptor 3
  • BR3
  • CD268 antigen
  • CD268
  • CVID4
  • tumor necrosis factor receptor superfamily member 13C
  • tumor necrosis factor receptor superfamily, member 13C

Background

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL-1, THANK, and zTNF4. BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. Two receptors, TACI and BCMA, for BAFF were originally identified. A third receptor was identified recently and designated BAFF-R and BR3 for BLyS receptor 3. Unlike BCMA and TACI, which bind to BAFF and April, BAFF-R/BR3 is specific for BAFF and plays a predominant role in BAFF induced B cell development and survival. BAFF and its receptors are involved in B cell associated autoimmune diseases, and activate NF-kB and c-jun N-terminal kinase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TNFRSF13C
Uniprot