BAFF/BLyS/TNFSF13B Antibody (2C11) Summary
TNFSF13B (AAH20674, 1 a.a. ~ 286 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.MDDSTEREQSRLTSCLKKREEMKLKECVSILPRKESPSVRSSKDGKLLAATLLLALLSCCLTVVSFYQVAALQGDLASLRAELQGHHAEKLPAGAGAPKAGLEEAPAVTAGLKIFEPPAPGEGNSSQNSRNKRAVQGPEETVTQDCLQLIADSETPTIQKGSYTFVPWLLSFKRGSALEEKENKILVKETGYFFIYGQVLYTDKTYAMGHLIQRKKVHVFGDELSLVTLFRCIQNMPETLPNNSCYSAGIAKLEE
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Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.4)
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
This antibody is useful for ELISA, Western Blot
This product is reactive against Human.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for BAFF/BLyS/TNFSF13B Antibody (2C11)
- ApoL related ligand TALL-1
- B lymphocyte stimulator
- BAFFB-cell activating factor
- B-cell-activating factor
- BLYSB-lymphocyte stimulator
- CD257 antigen
- Dendritic cell-derived TNF-like molecule
- TALL-1delta BAFF
- TALL1Delta4 BAFF
- TNF- and APOL-related leukocyte expressed ligand 1
- TNF and ApoL-related leukocyte expressed ligand 1
- TNF homolog that activates apoptosis
- tumor necrosis factor (ligand) superfamily, member 13b
- tumor necrosis factor (ligand) superfamily, member 20
- tumor necrosis factor ligand superfamily member 13B
- tumor necrosis factor superfamily, member 13b
- tumor necrosis factor-like protein ZTNF4
Members of the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BLyS (for B Lymphocyte Stimulator), TALL1 (for TNF- and ApoL- related Leukocyte-expressed Ligand), and THANK (for TNF Homologue that Activate Apoptosis, NFkB and c-jun N-terminal Kinase). BAFF/BLyS was characterized as a B cell stimulator since it induced B cell proliferation and immunoglobulin secretion. Two receptors for BAFF were recently identified and designated TACI and BCMA. BAFF also signals through a third TNF receptor BAFFR/BR3. BAFF and its receptors are involved in the development of systemic lupus erythaematosus and other B cell associated autoimmune diseases. Like TNFa and TRAIL, THANK was shown to activate NF-kB and c-jun N terminal kinase (JNK) and to induce apoptosis.
The human BAFF gene codes for a 285 amino acid type II transmembrane protein containing a 46 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 218 amino acid extracellular domain.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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