B7-2/CD86 Antibody (PO3.1) Summary
The immunogen for this antibody was CD86.
DC Maturation Marker
Protein A or G purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Flow Cytometry 1:10-1:1000
The PO3.1 antibody has been tested by flow cytometric analysis of resting and activated mouse splenocyte suspensions and can be used at less than or equal to 0.5 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
Aqueous, may contain carrier protein/stabilizer.
0.09% Sodium Azide
Protein A or G purified
Alternate Names for B7-2/CD86 Antibody (PO3.1)
- Activation B7-2 antigen
- B7-2 antigen
- B-lymphocyte activation antigen B7-2
- CD28 antigen ligand 2
- CD28LG2B7-2 antigen)
- CD86 antigen
- CD86 molecule
- CTLA-4 counter-receptor B7.2
- T-lymphocyte activation antigen CD86
The PO3.1 monoclonal antibody reacts with mouse CD86, an ~80 kDa surface receptor also known as B7-2. CD86 and CD80 are members of the B7 family of costimulatory molecules. CD86 is expressed at low level on B cells, macrophages, and dendritic cells and is upregulated on B cells through a variety of surface stimuli including the BCR complex, CD40 and some cytokine receptors. CD86 is also expressed by activated mouse T cells and thioglycolate-elicited peritoneal cells. In addition to CD80 (B7-1), CD86 is a counter-receptor for the T cell surface molecules CD28 and CD152 (CTLA-4). The interaction of CD86 with its ligands plays a critical role in T-B crosstalk, T cell costimulation, autoantibody production and Th2-mediated Ig production. The kinetics of upregulation of CD86 upon stimulation supports its major contribution during the primary phase of an immune response.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
Customers Who Viewed This Item Also Viewed...
Applications: Flow, IHC, CyTOF-ready, ELISA(Cap), ELISA(Det), Neut, ELISA(Sta)
Applications: WB, Flow, CyTOF-ready, ICC
Applications: WB, ELISA, PLA
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP, Flow-IC
Species: Hu, Mu, Rt, Po, Bv
Applications: WB, ICC/IF
Applications: Flow, Func, ICC/IF, IHC, IHC-Fr, IHC-P
Applications: WB, AgAct
Applications: Flow, CyTOF-ready, ICC
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Applications: WB, IP
Applications: Flow, Func
Publications for B7-2/CD86 Antibody (NBP1-43382) (0)
There are no publications for B7-2/CD86 Antibody (NBP1-43382).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for B7-2/CD86 Antibody (NBP1-43382) (0)
There are no reviews for B7-2/CD86 Antibody (NBP1-43382).
By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
- Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
- Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
- 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
FAQs for B7-2/CD86 Antibody (NBP1-43382) (0)
Additional B7-2/CD86 Products
Bioinformatics Tool for B7-2/CD86 Antibody (NBP1-43382)
Discover related pathways, diseases and genes to B7-2/CD86 Antibody (NBP1-43382). Need help?
Read the Bioinformatics Tool Guide
for instructions on using this tool.
Blogs on B7-2/CD86.
CD86 - I work in tandem with CD80
CD86 belongs to the immunoglobulin superfamily of proteins that drive innate and adaptive immune responses. It is an 80kD co-stimulatory molecule for the priming and activation of naive and memory T-cells, respectively. CD86 is expressed on activated... Read full blog post.