B7-2/CD86 Antibody (2D10) Summary
Mouse B cell lymphoma cell line 5C2
DC Maturation Marker
Mouse CD86, the B7-2 costimulatory molecule and a ligand for CD28 and CD152
Protein A or G purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Blocking/Neutralizing 50-200 molar excess
- ELISA 1:100-1:2000
- Flow Cytometry 1:10 - 1:1000
- Immunohistochemistry 1:10 - 1:500
- Immunohistochemistry-Frozen 1:10 - 1:500
- Immunoprecipitation 1:10 - 1:500
- In vitro assay
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
0.1M BBS (pH 8.2)
Protein A or G purified
Alternate Names for B7-2/CD86 Antibody (2D10)
- Activation B7-2 antigen
- B7-2 antigen
- B-lymphocyte activation antigen B7-2
- CD28 antigen ligand 2
- CD28LG2B7-2 antigen)
- CD86 antigen
- CD86 molecule
- CTLA-4 counter-receptor B7.2
- T-lymphocyte activation antigen CD86
CD86/B7-2 is an 80 kDa type I integral membrane protein and a member of the immunoglobulin superfamily of cell surface receptors. Along with CD80/B7-1, CD86 participates in T cell costimulation via interaction with CD28 and CD152/CTLA-4. It is expressed at very low density in normal tissues but is rapidly upregulated on stimulated B cells, monocytes and dendritic cells. Since CD86/B7-2 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. (1-9)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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Additional B7-2/CD86 Products
Bioinformatics Tool for B7-2/CD86 Antibody (NBP1-28197)
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Blogs on B7-2/CD86.
CD86 - I work in tandem with CD80
CD86 belongs to the immunoglobulin superfamily of proteins that drive innate and adaptive immune responses. It is an 80kD co-stimulatory molecule for the priming and activation of naive and memory T-cells, respectively. CD86 is expressed on activated... Read full blog post.