B7-1/CD80 RNAi Summary
CD80 antigen (CD28 antigen ligand 1, B7-1 antigen) (CD80), mRNA
This RNAi causes protein knockdown.
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for B7-1/CD80 RNAi
- Activation B7-1 antigen
- CD28LGB7-1 antigen)
- CD80 antigen
- CD80 molecule
- costimulatory factor CD80
- costimulatory molecule variant IgV-CD80
- CTLA-4 counter-receptor B7.1
- T-lymphocyte activation antigen CD80
Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene. The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo. Chimera RNAi has many advantages over the conventional siRNAs. First, it has been demonstrated to have reliable knock-down for over 10,000 human genes. Because the human genome is composed of an intricate, genetic network, chimera RNAis unique design has successfully obviated the off-target effects including microRNA-based influence. Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected. Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. RNAi are guaranteed
for 3 months from date of receipt.
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Product General Protocols
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Additional B7-1/CD80 Products
Bioinformatics Tool for B7-1/CD80 RNAi (H00000941-R01)
Discover related pathways, diseases and genes to B7-1/CD80 RNAi (H00000941-R01). Need help?
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Blogs on B7-1/CD80.
CD80: A co-stimulator of T cell activation
CD80 is a 60kD single chain type I transmembrane glycoprotein that is a member of the immunoglobulin family. CD80 is expressed on activated B- and T-lymphocytes, as well as a subpopulation of previously activated B-cells, but not on the majority of re... Read full blog post.