B7-1/CD80 Antibody (MEM-233) [Allophycocyanin]

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Flow Cytometry: B7-1/CD80 Antibody (MEM-233) [Allophycocyanin] [NB110-81741] - Surface staining of RAJI human Burkitt lymphoma cell line with anti-human CD80 (MEM-233) APC. Total viable cells were used for analysis.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB110-81741
    • Availability
      Product Discontinued

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B7-1/CD80 Antibody (MEM-233) [Allophycocyanin] Summary

Immunogen
Extracellular domain of human CD80 fused to human IgG1(Fc)
Localization
Cell Membrane
Specificity
The antibody MEM-233 reacts with CD80 (B7-1), a 60 kDa single chain type I glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CD80
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry 10 ul/100 ul of whole blood or 10^6 cells in suspension
Publications
Read Publication using NB110-81741.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS and 0.2% (w/v) high grade BSA (protease free)
Preservative
15mM Sodium Azide
Purity
Protein A purified

Alternate Names for B7-1/CD80 Antibody (MEM-233) [Allophycocyanin]

  • Activation B7-1 antigen
  • B7
  • B71
  • B7-1
  • BB1
  • CD28LG1
  • CD28LGB7-1 antigen)
  • CD80 antigen
  • CD80 molecule
  • CD80
  • costimulatory factor CD80
  • costimulatory molecule variant IgV-CD80
  • CTLA-4 counter-receptor B7.1
  • T-lymphocyte activation antigen CD80

Background

CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for B7-1/CD80 Antibody (NB110-81741)(1)

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Secondary Antibodies

 

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Bioinformatics Tool for B7-1/CD80 Antibody (NB110-81741)

Discover related pathways, diseases and genes to B7-1/CD80 Antibody (NB110-81741). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for B7-1/CD80 Antibody (NB110-81741)

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PTMs for B7-1/CD80 Antibody (NB110-81741)

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Research Areas for B7-1/CD80 Antibody (NB110-81741)

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Blogs on B7-1/CD80.

CD80: A co-stimulator of T cell activation
CD80 is a 60kD single chain type I transmembrane glycoprotein that is a member of the immunoglobulin family. CD80 is expressed on activated B- and T-lymphocytes, as well as a subpopulation of previously activated B-cells, but not on the majority of re...  Read full blog post.

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Bioinformatics

Gene Symbol CD80
Entrez