B220/CD45R Antibody (HIS24 (6B6))



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B220/CD45R Antibody (HIS24 (6B6)) Summary

Single cell suspension of rat peyers patches
Reacts with mature and precursor B lymphocytes. Weak reaction with marginal zone B cells and a small subset of T cells and CD45R.
Tissue culture supernatant
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.2M Tris/HCl (pH 7.4) and 5 - 10% fetal Bovine serum (FBS)
0.09% Sodium Azide
Tissue culture supernatant

Reactivity Notes

Reacts with Rat.


CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms (220, 205, 190, 180 kDa) which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognizing a common epitope on all of the isoforms are termed CD45 whilst those recognizing only individual isoforms are termed CD45RA or CD45RO etc.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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