Aurora C Antibody (10A7)

Images

 
Western Blot: Aurora C Antibody (10A7) [NBP1-47662] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Aurora C (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell ...read more
Immunocytochemistry/ Immunofluorescence: Aurora C Antibody (10A7) [NBP1-47662] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY Aurora C.
Immunohistochemistry-Paraffin: Aurora C Antibody (10A7) [NBP1-47662] - Staining of paraffin-embedded Kidney tissue using anti-Aurora C mouse monoclonal antibody.
Immunohistochemistry-Paraffin: Aurora C Antibody (10A7) [NBP1-47662] - Staining of paraffin-embedded endometrium tissue using anti-Aurora C mouse monoclonal antibody.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-47662
    • Availability
      Product Discontinued

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Aurora C Antibody (10A7) Summary

Immunogen
Protein expressed in 293T cell transfected with human AURKC expression vector
Specificity
This antibody is specific for Homo sapiens aurora kinase C (AURKC), transcript variant 1.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
AURKC
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • Immunocytochemistry/Immunofluorescence 1:100
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 1.0% BSA and 50% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Aurora C Antibody (10A7)

  • AIE2AIK3
  • ARK3Serine/threonine-protein kinase aurora-C
  • AurC
  • aurora kinase CAurora/IPL1/Eg2 protein 2
  • Aurora/IPL1-related kinase 3
  • aurora-C
  • Aurora-related kinase 3
  • EC 2.7.11
  • EC 2.7.11.1
  • serine/threonine kinase 13 (aurora/IPL1-like)
  • serine/threonine-protein kinase 13
  • STK13ARK-3

Background

This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol AURKC
Entrez