Aurora B Antibody

Images

 
Immunohistochemistry-Paraffin: Aurora B Antibody [NBP1-50318] - Analysis of anti-AURKB / Aurora-B antibody with human tonsil at concentration 10 ug/ml.
Immunohistochemistry-Paraffin: Aurora B Antibody [NBP1-50318] - Analysis of anti-AURKB / Aurora-B antibody with human skin at concentration 10 ug/ml.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC-P
Clonality
Polyclonal
Host
Sheep
Conjugate
Unconjugated
Concentration
0.105 mg/ml

Order Details

Aurora B Antibody Summary

Immunogen
Recombinant human His(6)-Aurora B [residues 1 - 344] expressed in insect cells.
Marker
Mitosis Marker
Specificity
Recognizes human Aurora B
Isotype
IgG
Clonality
Polyclonal
Host
Sheep
Gene
AURKB
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.2 ug/ml
  • Immunohistochemistry-Paraffin 10 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Purified antiserum with PBS
Preservative
0.1% Sodium Azide
Concentration
0.105 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Aurora B Antibody

  • Aik2
  • AIK2EC 2.7.11.1
  • AIM-1
  • AIM1Aik2
  • AIM-1STK-1
  • ARK2
  • ARK2ARK-2
  • AurB
  • AURKB
  • aurkb-sv2
  • Aurora- and IPL1-like midbody-associated protein 1
  • Aurora B
  • aurora kinase BSerine/threonine-protein kinase aurora-B
  • aurora kinase B-Sv1
  • aurora kinase B-Sv2
  • Aurora/IPL1-related kinase 2
  • aurora-1
  • aurora-B
  • Aurora-related kinase 2
  • EC 2.7.11
  • IPL1
  • serine/threonine kinase 12
  • serine/threonine-protein kinase 12
  • STK12
  • STK12aurkb-sv1
  • STK5

Background

Aurora B belongs to Serine/threonine kinase family, Aurora subfamily. Predicted molecular weight 39 kD. This kinase is highly expressed in thymus and many cancers and is also expressed in the spleen, lung, testis, colon, placenta and fetal liver. Aurora B is expressed during S and G2/M phase and is up regulated in cancer cells during M phase. Aurora B localizes to centromeres in early mitosis and then the spindle midzone in anaphase and is required for histone H3 phosphorylation, chromosome alignment, centrosome maturation, activation of the spindle assembly checkpoint and cytokinesis. The Poly6361 antibody recognizes human phospho-Aurora B (Thr232) and has been shown to be useful for immunoflorence staining. Survivin, Inner centromere protein, RasGAP, septin 1, Ga55, CDCA8

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol AURKB
Entrez
Uniprot