ATP7A Antibody

Images

 
Western Blot: ATP7A Antibody [NBP1-51275] - Lane1: Hela whole cell lysate. Lane2: NIH-3T3 whole cell lysate. Lane3: Rat brain tissue lysate.
Immunohistochemistry-Paraffin: ATP7A Antibody [NBP1-51275] - Human brain tissue.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-51275
    • Availability
      Product Discontinued

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ATP7A Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 620-670 of Human ATP7A.
Specificity
ATP7A (H640) pAb detects endogenous levels of ATP7A protein.
Clonality
Polyclonal
Host
Rabbit
Gene
ATP7A
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Immunohistochemistry (IHC) analyzes of ATP7A (H640) pAb in paraffin-embedded human brain tissue.
Theoretical MW
163 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ATP7A Antibody

  • ATPase, Cu++ transporting, alpha polypeptide
  • Copper pump 1
  • copper-transporting ATPase 1
  • Cu++-transporting P-type ATPase
  • DSMAX
  • EC 3.6.3
  • EC 3.6.3.4
  • MC1
  • Menkes disease-associated protein
  • Menkes syndrome
  • MK
  • MNKFLJ17790
  • OHS
  • SMAX3

Background

Copper-transporting ATPase 1 is an integral membrane protein cycling constitutively between the trans-golgi network and the plasma membrane. It may supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells.Defects in ATP7A are the cause of Menkes syndrome ; also known as kinky hair disease, an X-linked recessive disorder.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ATP7A