ATG9A Antibody

Product Discontinued

ATG9A Antibody Summary

• Immunogen: A synthetic peptide (CWHRRESDESGE) corresponding to the C-terminal of human APG9A (APG9L1) protein has been used as the immunogen.
• Specificity: IHC, WB and ELISA confirmed the specificity for ATG9A (APG9L1).
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ATG9A
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100-1:3000
  • Immunohistochemistry 1:100-1:3000
  • Immunohistochemistry-Paraffin
  • Western Blot 1:100-1:3000

Reactivity Notes

Human, rat. The peptide is homologous with the corresponding sequence derived from APG9A (APG9L1) protein in mouse, rat, S. cerevisiae, Macaca mulatta (monkey) and Canis familiaris (dog).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Whole antisera
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Unpurified
• Reconstitution Instructions: Reconstitute with 0.1 ml sterilized water.

Notes

Add diH20 for desired concentration.

Alternate Names for ATG9A Antibody

• APG9 autophagy 9-like 1 (S. cerevisiae)
• APG9 autophagy 9-like 1
• APG9L1APG9-like 1
• ATG9 autophagy related 9 homolog A (S. cerevisiae)
• autophagy 9-like 1 protein
• autophagy-related protein 9A
• FLJ22169
• mATG9
• MGD3208

Background

FUNCTION: Plays a role in autophagy. SUBCELLULAR LOCATION: Membrane; multi-pass membrane protein (Potential). ALTERNATIVE PRODUCTS: 3 named isoforms produced by alternative splicing. SIMILARITY: Belongs to the ATG9 family. IN YEAST: FUNCTION: Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Recruites ATG23 and ATG8 to the pre-autophagosomal structure. SUBUNIT: Interacts with ATG18, ATG2 and ATG23. SUBCELLULAR LOCATION: Membrane; multi-pass membrane protein. Preautophagosomal structure; preautophagosomal structure membrane; multi-pass membrane protein. Note=Pre-autophagosomal and other perivacuolar punctate structures. The proper trafficking of ATG9 between the pre-autophagosomal structure and the other punctate structures requires ATG2, ATG18, ATG23, the ATG1-ATG13 complex and the phosphatidylinositol 3-kinase complex I. SIMILARITY: Belongs to the ATG9 family.



This product is distributed on behalf of Biosensis Pty. Ltd. of Australia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ATG9A Antibody (R-160-100)(11)

Publications using R-160-100

• Cook KL, Shajahan AN, Warri A et al. Glucose-Regulated Protein 78 Controls Cross-talk between Apoptosis and Autophagy to Determine Antiestrogen Responsiveness Cancer Res 2012-07-01 [PMID: 22752300] (WB, Human)
• Kim H et al. Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147. 2006-01-01 [PMID: 16847258]
• Ota,T. Nat. Genet. 36 (1), 40-45. 2004-01-01 [PMID: 14702039]
• Tucker KA et al. J. Biol. Chem. 278:48445-48452. 2003-01-01 [PMID: 14504273]
• Lang T et al. J. Bacteriol. 182:2125-2133. 2000-01-01 [PMID: 10735854]
• Noda T et al. J. Cell Biol. 148:465-480. 2000-01-01 [PMID: 10662773]
• Jacq C et al. Nature 387:75-78. 1997-01-01 [PMID: 9169867]
• Delaveau TTD et al. Yeast 12:1587-1592. 1996-01-01 [PMID: 8972581]
• Harding TM et al. J. Biol. Chem. 271:17621-17624. 1996-01-01 [PMID: 8663607]
• Tsukada M, Ohsumi Y. FEBS Lett. 333:169-174. 1993-01-01 [PMID: 8224160]
• Harding TM et al. J. Cell Biol. 131:591-602. 1995-01-01 [PMID: 7593182]

Bioinformatics

• Gene Symbol: ATG9A
• Entrez:
  • 79065(Human)
  • 363254(Rat)
• Uniprot:
  • Q7Z3C6(Human)