Arylsulfatase A/ARSA Antibody

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Western Blot: ARSA Antibody [NBP1-54400] - Titration: 0.2-1 ug/ml, Positive Control: THP-1 cell lysate.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-54400
    • Availability
      Product Discontinued

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Arylsulfatase A/ARSA Antibody Summary

Immunogen
Synthetic peptides corresponding to ARSA(arylsulfatase A) The peptide sequence was selected from the middle region of ARSA. Peptide sequence KQLQLLKAQLDAAVTFGPSQVARGEDPALQICCHPGCTPRPACCHCPDPH.
Clonality
Polyclonal
Host
Rabbit
Gene
ARSA
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
This is a rabbit polyclonal antibody against ARSA and was validated on Western blot.
Theoretical MW
52 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 2% Sucrose
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for Arylsulfatase A/ARSA Antibody

  • ARSA
  • Arylsulfatase A
  • ASA
  • Cerebroside 3-sulfatase
  • Cerebroside-sulfatase
  • EC 3.1.6
  • EC 3.1.6.8
  • MLD

Background

ARSA hydrolyzes cerebroside sulfate. Defects in ARSA are a cause of leukodystrophy metachromatic (MLD).The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Multiple alternatively spliced transcript variants, one of which encodes a distinct protein, have been described for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ARSA
Entrez
Uniprot