Arrestin 3 Antibody

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Western Blot: Arrestin 3 Antibody [NBP1-19629] - Analysis of Arrestin-C (E374) pAb at 1:500 dilutionLane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate
Immunohistochemistry-Paraffin: Arrestin 3 Antibody [NBP1-19629] - Analyzes of paraffin-embedded human tonsil carcinoma tissue at 1:50.showing cytoplasmic and nucleus staining. Negative control (the right) Using PBS ...read more
Western Blot: Arrestin 3 Antibody [NBP1-19629] - Arrestin 3 Antibody extracts from LOVO cells.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-19629
    • Availability
      Product Discontinued

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Arrestin 3 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 350-400 of Human Arrestin-C.
Clonality
Polyclonal
Host
Rabbit
Gene
ARR3
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunocytochemistry/Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Western blot (WB) analysis of Arrestin-C (E374) pAb in extracts from LOVO cells.
Theoretical MW
43 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Arrestin 3 Antibody

  • arrestin 3, retinal (X-arrestin)
  • arrestin 4
  • arrestin-C
  • ARRXcArr
  • CAR
  • C-arrestin
  • Cone arrestin
  • Retinal cone arrestin-3
  • X-arrestin

Background

Members of Arrestin/beta-Arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters or sensory signals. Arrestin-C, also known as retinal cone Arrestin-3, X-Arrestin or cArr, is a member of the Arrestin family of proteins. It is predominantly found in the retina and pineal gland and localizes to the inner and outer segments of red-, green- and blue-cone photoreceptors and the inner plexiform regions. Two Arrestin-C isoforms exist due to alternative splicing. Isoform 1 is the mature full length protein and isoform 2 is truncated, ending with an arginine for amino acid residue 359. Arrestin-C expression is stimulated by retinoic acid. It may play a role in retina-specific signal transduction and bind to photoactivated-phosphorylated red/green opsins. In addition, Arrestin-C forms homodimers and oligomers with beta-Arrestins and may regulate beta-Arrestin mediated signaling.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ARR3
Entrez
Uniprot