Aquaporin-4 Antibody

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Product Details

Summary
Product Discontinued
View other related Aquaporin-4 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-30859
    • Availability
      Product Discontinued

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Aquaporin-4 Antibody Summary

Immunogen
A synthetic peptide from the c-terminal region of human Aquaporin 4 (AQP4) conjugated to an immunogenic carrier protein was used as the immunogen.
Marker
Astrocytes Marker
Specificity
Appears to be specific for AQP4.
Clonality
Polyclonal
Host
Rabbit
Gene
AQP4
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:300-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

Human. Other species not yet tested.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
No Preservative
Concentration
LYOPH
Purity
Unpurified
Reconstitution Instructions
Reconstitute with 0.1 ml sterilized water to desired concentration.

Alternate Names for Aquaporin-4 Antibody

  • aquaporin 4
  • MGC22454

Background

In skeletal muscle, AQP4 (aquaporin 4 also known as mercurial insensitive water channel), localizes to the sarcolemma of fast-twitch muscle fibers. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation and the

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

Additional Aquaporin-4 Products

Bioinformatics Tool for Aquaporin-4 Antibody (NBP1-30859)

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Bioinformatics

Gene Symbol AQP4
Entrez