APLP-1 Antibody (354008) [Alexa Fluor® 700]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
354008
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 700
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

APLP-1 Antibody (354008) [Alexa Fluor® 700] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human APLP-1
Gln34-Glu580 (predicted)
Accession # P51693
Specificity
Detects human APLP-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross‑reactivity with recombinant mouse APLP‑1 is observed and no cross-reactivity with recombinant human APLP‑2 is observed.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
APLP1
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells
Application Notes
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Preservative
0.09% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for APLP-1 Antibody (354008) [Alexa Fluor® 700]

  • amyloid beta (A4) precursor-like protein 1
  • amyloid precursor-like protein 1
  • amyloid-like protein 1
  • APLP1
  • APLP-1
  • APLPAPLP-1

Background

APLP-1 is a transmembrane metalloprotein that is expressed in central neurons. Similar to APP and APLP-2, APLP-1 is susceptible to cleavage by various secretases, generating multiple fragments from the extracellular and intracellular domains. These include peptides similar to the amyloidogenic A beta peptides and a cytoplasmic fragment that associates with Fe65 family proteins and functions as a transcriptional activator. The extracellular domain contains heparin and collagen binding regions and shares 89% amino acid sequence identity between human and mouse.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for APLP-1 Antibody (FAB3129N) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 FAB3129U
Alexa Fluor 405 FAB3129V
Alexa Fluor 488 FAB3129G
Alexa Fluor 594 FAB3129T
Alexa Fluor 647 FAB3129R
Alexa Fluor 700 FAB3129N
Alexa Fluor 750 FAB3129S

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Contact Information

Learn the difference between western blot and simple western

Product PDFs

Calculators

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Bioinformatics

Gene Symbol APLP1