Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
Immunogen affinity purified
Manufactured by SDIX's proprietary Genomic Antibody Technology. GAT FAQs.
Alternate Names for Angiopoietin-like Protein 4/ANGPTL4 Antibody
Angiopoietin like Protein 4
Angiopoietin-like Protein 4
ARP4fasting-induced adipose factor
FIAFhepatic angiopoietin-related protein
Hepatic fibrinogen/angiopoietin-related protein
peroxisome proliferator-activated receptor (PPAR) gamma inducedangiopoietin-related protein
PGARangiopoietin-related protein 4
PPARG angiopoietin related protein
This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
FAQs for Angiopoietin-like Protein 4/ANGPTL4 Antibody (26200002). (Showing 1 - 1 of 1 FAQs).
Does this AB react with the full length human ANGPTL4? Was a cross-reaction to N-terminal part absent? What is the working concentration of this AB in ELISA? Does this antibody react with C-terminal in WB also?
In regards to this product it should detect the full length endogenous protein, but was raised solely from a sequence containing amino acids located at the C-Terminal region. The concentration is lot specific. If you have a specific lot I can try to find out a good working range for ELISA. Typically this can vary greatly because of the type of assay will be dependent on what you are trying to measure in your experiment. It can range from 1:1000-1:10000 or greater. This antibody has not been tested in Western blot, so I do not have additional data on that assay.
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