Angiopoietin-like Protein 4/ANGPTL4 Antibody (1A12)

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Immunoprecipitation: Angiopoietin-like Protein 4/ANGPTL4 Antibody (1A12) [H00051129-M02] - Analysis of ANGPTL4 transfected lysate using anti-ANGPTL4 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, IP
Clone
1A12
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Angiopoietin-like Protein 4/ANGPTL4 Antibody (1A12) Summary

Immunogen
ANGPTL4 (AAH23647, 26 a.a. ~ 407 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.GPVQSKSPRFASWDEMNVLAHGLLQLGQGLREHAERTRSQLSALERRLSACGSACQGTEGSTDLPLAPESRVDPEVLHSLQTQLKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPVDPAHNVSRLHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDW
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
ANGPTL4
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunoprecipitation
Application Notes
This antibody is useful for ELISA

Reactivity Notes

This product is reactive against Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Angiopoietin-like Protein 4/ANGPTL4 Antibody (1A12)

  • Angiopoietin like Protein 4
  • angiopoietin-like 4
  • Angiopoietin-like Protein 4
  • ANGPTL4
  • ARP4fasting-induced adipose factor
  • FIAF
  • FIAFhepatic angiopoietin-related protein
  • Hepatic fibrinogen/angiopoietin-related protein
  • HFARP
  • HFARPANGPTL2
  • NL2
  • peroxisome proliferator-activated receptor (PPAR) gamma inducedangiopoietin-related protein
  • PGAR
  • PGARangiopoietin-related protein 4
  • pp1158
  • PPARG angiopoietin related protein

Background

This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ANGPTL4
Entrez
Uniprot