ALX3 Antibody


Western Blot: ALX3 Antibody [NB100-92297] - Analysis in extracts from 293 cells.
Immunohistochemistry-Paraffin: ALX3 Antibody [NB100-92297] - Paraffin-embedded human kidney carcinoma tissue at 1:50,showing nucleus staining. Negative control (the right) Using PBS instead of primary antibody, more

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ALX3 Antibody Summary

Synthetic peptide, corresponding to amino acids 171-220 of Human ALX3.
ALX3 (R203)Antibody detects endogenous levels of ALX3 (R203) protein.
Immunogen affinity purified
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  • Western Blot 1:500-1:1000
  • Immunocytochemistry/Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Western blot (WB) analysis of ALX3 (R203) pAb in extracts from 293 cells.
Theoretical MW
36 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2)
0.05% Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Alternate Names for ALX3 Antibody

  • ALX homeobox 3
  • aristaless-like homeobox 3
  • homeobox protein aristaless-like 3
  • MGC138212
  • MGC141988
  • Proline-rich transcription factor ALX3


Aristaless-related genes are a group of paired-related homeobox genes which play a role in regulating vertebrate embryogenesis. The homeodomain transciption factor aristaless-like 3 (ALX3) is expressed in mouse embryos from 8 days of gestation, predominantly in neural crest-derived mesenchyme and in lateral plate mesoderm. Expression analysis of human and mouse tissue reveals predominant ALX3 expression in brain tissue. The Alx3 gene maps to chromosome 1p23-p13 and encodes a 343 amino acid protein. Preferential methylation of Alx3 occurs in advanced-stage neuroblastoma and may repress ALX3 expression. Treatment with the methylation inhibitor 5-aza-2'-deoxycytidine restores ALX3 expression. Alx3 (-) mice lack a phenotype distinct from wild-type mice, however Alx3/Alx4 double mutants demonstrate severe craniofacial abnormalities not present in Alx4 single mutants. Specifically, Alx3/Alx4 double mutant newborn mice have cleft nasal regions in addition to malformation of other neural crest-derived skull structures.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Gene Symbol ALX3