ALS2CR2 Antibody

Product Discontinued

ALS2CR2 Antibody Summary

• Immunogen: Synthetic peptide from human STRADB.
• Specificity: synthetic peptide corresponding to amino acids near the center of human ILPIP
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: STRADB
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 10 ug/ml
  • Western Blot 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for ALS2CR2 Antibody

• ALS2CR2candidate 2
• Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein
• CALS-21MGC102916
• ILP-interacting protein
• ILPIPSTRAD beta
• Pseudokinase ALS2CR2
• STE20-related kinase adaptor beta

Background

ILPIP (ILP-interacting protein) has recently been shown to interact with XIAP, a member of the IAP (Inhibitor of Apoptosis) protein family. Together, these two proteins synergistically activate the TAK1/JNK1 signal transduction pathway, which acts to protect against the interleukin-1b converting enzyme of Fas-induced apotosis. This protein was independently isolated and characterized as polyploidy-associated protein kinase (PAPK), a member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival, suggesting that its protective role may be a function of its kinase activity. Although two mRNA sequences have been isolated, only the shorter isoform has been observed.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: STRADB
• Entrez:
  • 55437(Human)
  • 227154(Mouse)
  • 501146(Rat)
• Uniprot:
  • Q9C0K7(Human)