alpha-Synuclein Antibody (2B2D1)

Images

 
Western Blot: Synuclein-alpha Antibody (2B2D1) [NB110-60492] - Figure 1: Western blot analysis using anti-human monoclonal antibody against truncated recombinant protein.
Immunohistochemistry: Synuclein-alpha Antibody (2B2D1) [NB110-60492] - Figure 2: Immunohistochemical analysis of paraffin-embedded human glioma tissue, showing membrane localization, using alpha-Synuclein Antibody ...read more

Product Details

Summary
Product Discontinued
View other related alpha-Synuclein Primary Antibodies

Order Details


    • Catalog Number
      NB110-60492
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

alpha-Synuclein Antibody (2B2D1) Summary

Immunogen
Ni-NTA purified truncated recombinant alpha-Synuclein Antibody (2B2D1) expressed in E. Coli strain BL21 (DE3)
Specificity
alpha-Synuclein Antibody (2B2D1)
Clonality
Monoclonal
Host
Mouse
Gene
SNCA
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Ascites
Preservative
0.03% Sodium Azide
Purity
Unpurified

Alternate Names for alpha-Synuclein Antibody (2B2D1)

  • alpha-Synuclein
  • Lewy body) 4
  • MGC110988
  • NACP
  • non A-beta component of AD amyloid
  • Non-A beta component of AD amyloid
  • Non-A4 component of amyloid precursor
  • non-A4 component of amyloid
  • PARK1
  • PARK4
  • PD1
  • SNCA
  • synuclein, alpha (non A4 component of amyloid precursor)
  • Synuclein-alpha

Background

Alpha-synuclein (SNCA), with 140-amino acid protein (about 15kDa), belongs to the synuclein family, which also includes beta- and gamma-synuclein. SNCA is a soluble protein, expressed principally in the brain but also expressed in low concentrations in all tissues examined (except liver). SNCA is implicated in the regulation of dopamine release and transport. The triplication of the SNCA can cause Parkinson disease (PD) and diffuse Lewy body disease within the same kindred. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Immunohistochemistry for SNCA has become the histological technique of choice for the diagnosis for Parkinson's disease, Dementia with Lewy bodies and Multiple System Atrophy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-25162
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
NB300-268
Species: Hu, Mu, Bv, Ce
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP
NBP1-90342
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
NB300-270
Species: Hu, Mu, Rt, Ch
Applications: WB, Simple Western, ICC/IF, IP, In vitro
NB300-109
Species: Hu, Mu, Rt, Dr, I, Ma
Applications: WB, Simple Western, ICC/IF, IHC, IHC-Fr, IHC-P, IF, IHC-FrFl
NBP2-13075
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP, IHC-FrFl
NBP2-55955
Species: Hu
Applications: ICC/IF, IHC-P
BC100-494
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP, PEP-ELISA
NB600-1160
Species: Hu, Mu, Rt, Po, Bv
Applications: WB, Simple Western, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P
AF5745
Species: Hu
Applications: WB, IHC
NB100-56703
Species: Hu, Mu
Applications: WB, IHC, IHC-Fr
NBP1-54899
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-Fr
H00005071-M01
Species: Hu, Rt
Applications: WB, ELISA, ICC/IF
NB100-56605
Species: Av, Bv, Sh
Applications: WB
NB300-749
Species: Hu, Mu, Rt, Pm
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP
NBP1-50811
Species: Hu
Applications: WB, ELISA, IA, S-ELISA
NBP2-15895
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
NB600-534
Species: Hu, Po, Vi
Applications: WB, ELISA, Flow, IHC, IHC-Fr, IHC-P, In vitro, RIA

Publications for alpha-Synuclein Antibody (NB110-60492) (0)

There are no publications for alpha-Synuclein Antibody (NB110-60492).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for alpha-Synuclein Antibody (NB110-60492) (0)

There are no reviews for alpha-Synuclein Antibody (NB110-60492). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for alpha-Synuclein Antibody (NB110-60492). (Showing 1 - 1 of 1 FAQ).

  1. I'm looking for an alpha-Synuclein antibody with an epitope located in the first half (N-terminus) of the protein - preferably a monoclonal antibody. Can you help me with that?
    • Please take a look at NB110-57475. It has been validated for human, rat and mouse and the applications ICC and WB and the epitope it detects is in the N terminal.

Secondary Antibodies

 

Isotype Controls

Additional alpha-Synuclein Antibody (2B2D1) Products

Related Products by Gene

Bioinformatics Tool for alpha-Synuclein Antibody (NB110-60492)

Discover related pathways, diseases and genes to alpha-Synuclein Antibody (NB110-60492). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for alpha-Synuclein Antibody (NB110-60492)

Discover more about diseases related to alpha-Synuclein Antibody (NB110-60492).
 

Pathways for alpha-Synuclein Antibody (NB110-60492)

View related products by pathway.

PTMs for alpha-Synuclein Antibody (NB110-60492)

Learn more about PTMs related to alpha-Synuclein Antibody (NB110-60492).

Blogs on alpha-Synuclein.

The role of Parkin and autophagy in retinal pigment epithelial cell (RPE) degradation
The root of Parkinson’s disease (PD) points to a poorly regulated electron transport chain leading to mitochondrial damage, where many proteins need to work cohesively to ensure proper function.  The two key players of this pathway are PINK1,...  Read full blog post.

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our alpha-Synuclein Antibody (2B2D1) and receive a gift card or discount.

Bioinformatics

Gene Symbol SNCA
Entrez