alpha-Smooth Muscle Actin Antibody

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Western Blot: alpha-Smooth Muscle Actin Antibody [NBP1-18879] - Whole cell lysate from HeLa, 293T and mouse NIH3T3 cells.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-18879
    • Availability
      Product Discontinued

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alpha-Smooth Muscle Actin Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to an N-terminal region of human alpha smooth muscle actin using the numbering given in entry NP_001604.1 (GeneID 59).
Marker
Mesenchymal Cell Marker
Clonality
Polyclonal
Host
Rabbit
Gene
ACTA2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 1:10-1:500

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for alpha-Smooth Muscle Actin Antibody

  • AAT6
  • ACTA2
  • Actin alpha 2
  • actin, alpha 2, smooth muscle, aorta
  • actin, aortic smooth muscle
  • ACTSA
  • ACTVS
  • alpha 2 actin
  • alpha SMA
  • alpha smooth muscle actin
  • alpha-actin-2
  • alpha-SMA
  • alphaSmooth Muscle Actin
  • alpha-Smooth Muscle Actin
  • a-sma
  • Cell growth-inhibiting gene 46 protein
  • growth-inhibiting gene 46
  • MYMY5
  • SMA
  • smooth muscle actin

Background

The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional alpha-Smooth Muscle Actin Products

Bioinformatics Tool for alpha-Smooth Muscle Actin Antibody (NBP1-18879)

Discover related pathways, diseases and genes to alpha-Smooth Muscle Actin Antibody (NBP1-18879). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for alpha-Smooth Muscle Actin Antibody (NBP1-18879)

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Pathways for alpha-Smooth Muscle Actin Antibody (NBP1-18879)

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PTMs for alpha-Smooth Muscle Actin Antibody (NBP1-18879)

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Research Areas for alpha-Smooth Muscle Actin Antibody (NBP1-18879)

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Blogs on alpha-Smooth Muscle Actin.

Alpha-smooth muscle actin and the modulation of endothelial and epithelial cell biology
Actin is essential for a wide range of cell functions, ranging from cell division and chromatin remodeling to vesicle trafficking and maintenance of cellular structure. In fact, mislocalization of actin to cell junctions during development leads t...  Read full blog post.

Understanding Actin Alpha 2 Smooth Muscle
Actins are extremely highly conserved structural proteins found in all eukaryotic cell cytoskeletons that govern cell structure, movement, and shape integrity. Six distinct actin isoforms, each encoded by a different gene and developmentally-regulated...  Read full blog post.

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Bioinformatics

Gene Symbol ACTA2
Entrez
Uniprot