alpha 2-Macroglobulin-like 1/A2ML1 Overexpression Lysate (Denatured)

Images

 
Western Blot: A2ML1 Overexpression Lysate [H00144568-T01] - Lane 1: A2ML1 transfected lysate (17.49 KDa) Lane 2: Non-transfected lysate.
Western Blot: A2ML1 Overexpression Lysate [H00144568-T01] - A2ML1 transfected lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB

Order Details

alpha 2-Macroglobulin-like 1/A2ML1 Overexpression Lysate (Denatured) Summary

Description
Pasmid: pCMV-A2ML1 full-length
Gene
A2ML1

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for alpha 2-Macroglobulin-like 1/A2ML1

Type
Overexpression
Protein State
Denatured

Notes

Quality control test: Transient overexpression cell lysate was tested with Anti-A2ML1 antibody by Western Blots.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for alpha 2-Macroglobulin-like 1/A2ML1 Overexpression Lysate (Denatured)

  • A2ML1
  • alpha 2Macroglobulin like 1
  • alpha 2-Macroglobulin-like 1
  • alpha-2-macroglobulin-like 1
  • alpha-2-macroglobulin-like protein 1
  • C3 and PZP-like, alpha-2-macroglobulin domain containing 9
  • CPAMD9

Background

The alpha-macroglobulin (AM) superfamily of proteins contains both complement components and protease inhibitors, including A2M (MIM 103950) and A2ML1. AM proteins display a unique trap mechanism of inhibition, by which the AM inhibitor undergoes a major conformational change upon its cleavage by a protease, thus trapping the protease and blocking it from subsequent substrate binding (Galliano et al., 2006 [PubMed 16298998]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Video Protocols

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Bioinformatics

Gene Symbol A2ML1
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