ALK-7/Activin Receptor Type 1C Antibody

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Western Blot: Activin A Receptor Type IC Antibody [NBP1-69657] - This Anti-ACVR1C antibody was used in Western Blot of Fetal Brain tissue lysate at a concentration of 1ug/ml.

Order Details


    • Catalog Number
      NBP1-69657
    • Availability
      Product Discontinued

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ALK-7/Activin Receptor Type 1C Antibody Summary

Immunogen
Synthetic peptides corresponding to ACVR1C(activin A receptor, type IC) The peptide sequence was selected from the N terminal of ACVR1C. Peptide sequence QVFCHSSNNVTKTECCFTDFCNNITLHLPTASPNAPKLGPMELAIIITVP.
Clonality
Polyclonal
Host
Rabbit
Gene
ACVR1C
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
This is a rabbit polyclonal antibody against ACVR1C and was validated on Western blot.
Theoretical MW
55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 2% Sucrose
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for ALK-7/Activin Receptor Type 1C Antibody

  • activin A receptor, type IC
  • Activin receptor type IC
  • activin receptor type-1C
  • Activin receptor-like kinase 7
  • Activin RIC
  • ACTR-IC
  • ACVR1C
  • ACVRLK7
  • ALK7
  • ALK-7
  • ALK7ALK-7
  • EC 2.7.11
  • EC 2.7.11.30

Background

ACVR1C is a type I receptor for the TGFB family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM].

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ACVR1C
Entrez
Uniprot