Aiolos/IKZF3 Antibody

Images

 
Western Blot: Aiolos/IKZF3 Antibody [H00022806-B01P] - Analysis of IKZF3 expression in transfected 293T cell line by IKZF3 polyclonal antibody. Lane 1: ZNFN1A3 transfected lysate(55.99 KDa). Lane 2: Non-transfected ...read more
Immunohistochemistry-Paraffin: Aiolos/IKZF3 Antibody [H00022806-B01P] - Analysis of purified antibody to IKZF3 on formalin-fixed paraffin-embedded human tonsil. (antibody concentration 3 ug/ml)
Western Blot: Aiolos/IKZF3 Antibody [H00022806-B01P] - IKZF3 MaxPab polyclonal antibody. Western Blot analysis of IKZF3 expression in Jurkat.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC, IHC-P
Clonality
Polyclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Aiolos/IKZF3 Antibody Summary

Immunogen
IKZF3 (AAH32707.1, 1 a.a. ~ 509 a.a) full-length human protein.MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDDSMKVKDEYSERDENVLKSEPMGNAEEPEIPYSYSREYNEYENIKLERHVVSFDSSRPTSGKMNCDVCGLSCISFNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHTGEKPFKCHLCNYACQRRDALTGHLRTHSVEKPYKCEFCGRSYKQRSSLEEHKERCRTFLQSTDPGDTASAEARHIKAEMGSERALV
Specificity
IKZF3 - IKAROS family zinc finger 3 (Aiolos),
Isotype
IgG
Clonality
Polyclonal
Host
Mouse
Gene
IKZF3
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control. Has also been used for immunohistochemistry (paraffin).

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Aiolos/IKZF3 Antibody

  • AIO
  • Aiolos
  • IKAROS family zinc finger 3 (Aiolos)
  • Ikaros family zinc finger protein 3
  • IKZF3
  • zinc finger protein Aiolos
  • ZNFN1A3
  • ZNFN1A3subfamily 1A, 3 (Aiolos)

Background

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol IKZF3
Entrez
Uniprot